Nouvelle approche thérapeutique du lymphome malin non hodgkinien orbitaire

Benabid, L; Desablens, B; Defossez, T.; Malthieu, D; Milazzo, S.; Turut, P

doi:10.1016/s0181-5512(05)80991-x

Cited by 7 publications

(1 citation statement)

References 8 publications

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“…Combination chemotherapy with CHOP (cyclophosphamide, doxorubicin, vincristine and prednisolone) is quite efficacious, while addition of intravenous rituximab (anti CD 20 monoclonal antibody) in the regimen helps in rapid remission with good results. 13,14 So, total or subtotal excision of the mass followed by radio-therapy and or chemotherapy has a better outcome in patients with large mass However, radiation exposure predisposes to the development of cataracts after 3 -8 years though The role of radiotherapy in DLCL is unclear. So, from the literature we can conclude that if CD20 is positive then R-CHOP is most efficacious but NHL without CD20 positive patients treatment should be initiated with CHOP regimen.…”

Section: Discussionmentioning

confidence: 99%

Ocular Manifestation As Earliest Presentation Of Non-Hodgkin’s Lymphoma, Mimicking Multiple Chalazia: A Rare Case Report

Chaudhuri¹

2020

DJO

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Primary orbital Non-Hodgkin's lymphoma (NHL) is very rare. This 40 year old female patient presented with small multiple smooth swellings on upper and lower conjunctival fornix and in subsequent visits she develops swelling arising from both side lacrimal sac location. MRI brain and orbit suggested multiple oval shaped lesions noted at retro-bulbar , medial and lateral canthus of both eyes and periorbital area without any bony destruction. Biopsy confirmed it to be a case of primary non-Hodgkin's lymphoma. She was given 6 cycles of chemotherapy with CHOP. The patient is now asymptomatic 2 months after the last cycle of the chemotherapy.

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Section: Discussionmentioning

confidence: 99%