Notes - Ketone Condensations Using Sulfonic Acid Ion Exchange Resin

Chemical reactivity of the tryptophan/acetone/DMSO triad system and its potential applications in nanomaterial synthesis

“…Initially, we propose that acetone undergoes self-aldol condensation, a reaction that conventionally necessitates a strong acid or base catalyst. 32,33 In our specic system utilizing DMSO as the solvent, we hypothesize that L-tryptophan (1) facilitates the self-aldol condensation of acetone (2), ultimately leading to the formation of MO (3), an a,b-unsaturated ketone (Scheme 1).…”

AlCl3-Mediated Aldol Cyclocondensation of 1,6- and 1,7-Diones to Cyclopentene and Cyclohexene Derivatives

“…Therefore, the water formed in this aldol condensation is removed as Al(OH) 3 and HCl, thus driving the reaction irreversibly. This is in contrast to the usual acid-catalyzed aldol condensation, where dehydration is done by heating …”

Brønsted acid-surfactant (BAS) catalysed cyclotrimerization of aryl methyl ketone

“…Owing to these facts 1, 3, 5-triarylbenzenes are synthesized by applying numerous strategies and using different methodologies. The most general approach of 1,3,5-triarylbenzene synthesis is triple condensation of aryl methyl ketones 9 and alkynes by incorporating different catalysts such as transition metal complexes (Nb 10 , TiCl 3 (OTf) 18 ) and solid acids 19 . Alternative methods include cross-coupling reactions involving 1,3,5-trihalobenzenes with organometallic moieties, catalysed by metals 20 .…”