Brønsted acid-surfactant (BAS) catalysed cyclotrimerization of aryl methyl ketone

Abstract

A brønsted acid-surfactant catalysed and simple, mild, metal catalyst free and chemo-selective method has been developed for synthesis of 1, 3, 5-triaryl benzenes from aryl methyl ketones. The advantages of this protocol subsume green and sustainable reaction medium, mild reaction conditions, easy product recovery and its good yields.

p‐Dodecylbenzenesulfonic Acid: An Efficient Brønsted Acid‐Surfactant‐Combined Catalyst to Carry out Diverse Organic Transformations in Aqueous Medium

“…1,3,5‐Triaryl benzenes ( 25 ) were generally synthesized via the triple condensation reactions of acetophenones ( 10 a ) using various catalysts that include sulfated tungstate, p ‐TsOH.H 2 O, thionyl chloride, TiCl 4 , TiCl 3 (OTf) etc in absence or presence of organic solvents. In 2012, Phatangare et al . developed a simple, convenient and aqueous mediated protocol for the synthesis of a series of1,3,5‐triaryl benzene derivatives ( 25 ) using p ‐dodecylbenzenesulfonic acid as an efficient metal‐free brønsted acid‐surfactant combined catalyst at 130–135 °C(Scheme ).…”

n-Dodecylbenzene Sulfonic Acid (DBSA) as a Novel Brønsted Acid Catalyst for the Synthesis of Bis(indolyl)methanes and Bis(4-hydroxycoumarin-3-yl)methanes in Water

“…In this context, we are trying to design a protocol that uses micellar media in aqueous condition [31][32][33]. Present work underlines the effectiveness of micellar media in synthesis of bis(indolyl)methanes and bis(4-hydroxycoumarin-3-yl)methanes (Scheme 1).…”