Not all LGE is the same. Scar contrast volume of distribution is lower in HCM than in infarction

Abstract

Figure 1 FLASH T1 mapping in apical HCM and MI with regions of interest drawn in the blood (aorta), areas of late gadolinium enhancement (LGE) and remote myocardium in MI.

Not all LGE is the same. Scar contrast volume of distribution is lower in HCM than in infarction

“…A prospective study of patients with HCM (n=58, n=16 with LGE in the interrogated slice) and acute myocardial infarction (n=19), who had LGE and EQ-CMR within the region of LGE. T1 of blood and myocardium were measured using multi flip angle T1 FLASH IR maps at increasing inversion time before and after reaching contrast equilibrium [1]. Regions of interest were drawn in the aorta, remote myocardium and myocardium with LGE (see Figure 1).…”

“…We hypothesized that LGE in different disease processes would have different degrees of interstitial expansion. We used equilibrium contrast CMR (EQ-CMR) 1 , to measure the degree of interstitial expansion by measuring the volume of distribution of contrast, Vd(m).…”