Nosocomial outbreak of disseminated orf infection in a burn unit, Gaziantep, Turkey, October to December 2012

Midilli, Kenan; Erkılıç, Ahmet; Kuşkucu, Mert Ahmet; Analay, H; Erkılıç, Suna; Benzonana, Nur; Yıldırım, Mehmet; Mülayim, K; Acar, Hakan; Ergönül, Önder

doi:10.2807/ese.18.11.20425-en

Cited by 32 publications

(33 citation statements)

References 7 publications

(8 reference statements)

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“…The patient’s history of residence near sheep and cows is a suspicious exposure risk; however, there were no reports of any animals that exhibited clinical signs or symptoms suggestive of orf virus infection in the weeks prior to illness in the patient. Transmission through confirmed infectious fomites has been a cause in previous documented orf virus infection cases associated with burn patients [13]; however, in the case of this burn patient, it is unknown whether the infection of the harvest and burn sites were due to concurrent infection from a common animal or fomite source or whether virus transmission was the direct result of the grafting process (ie, transmission of orf virus from the infected skin-graft harvest site to the susceptible skin-graft recipient site).…”

Section: Discussionmentioning

confidence: 99%

“…Parapoxvirus infections are generally self-limiting; however, burn patients are uniquely at risk for complicated orf virus infections because of the breakdown of the epidermal barrier [13, 14]. In rare instances, lesions can be disseminated and have a complicated recovery compounded by secondary skin infections requiring medical intervention [13].…”

Section: Discussionmentioning

confidence: 99%

“…In rare instances, lesions can be disseminated and have a complicated recovery compounded by secondary skin infections requiring medical intervention [13]. Orf virus lesions can develop into large, exophytic lesions (giant orf) that can spread beyond the initial sites of inoculation in immunocompromised hosts [9].…”

Section: Discussionmentioning

confidence: 99%

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Unique Presentation of Orf Virus Infection in a Thermal-Burn Patient After Receiving an Autologous Skin Graft

et al. 2016

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We describe a burn patient who developed skin lesions on her skin-graft harvest and skin-graft recipient (burn) sites. Orf virus infection was confirmed by a combination of diagnostic assays, including molecular tests, immunohistochemical analysis, pathologic analysis, and electron microscopy. DNA sequence analysis grouped this orf virus isolate among isolates from India. Although no definitive source of infection was determined from this case, this is the first reported case of orf virus infection in a skin graft harvest. Skin graft recipients with exposures to animals may be at risk for this viral infection.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Unique Presentation of Orf Virus Infection in a Thermal-Burn Patient After Receiving an Autologous Skin Graft

et al. 2016

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“…Alian ve arkadaşları (17), orf sonrası erythema multiforme ve büllöz pemfigoid benzeri erüpsiyon gibi nadir gelişen komplikasyonları akılda tutmamız gerektiğini bildirmiştir. Midilli ve arkadaşları (18) ise yanıklı 13 hastada orfun nozokomiyal bir salgına yol aça-bileceğini göstermiş ve salgını önlemede hijyen kurallarına uyumun ve standard infeksiyon kontrol önlemlerinin alınma-sının önemini vurgulamıştır.…”

Section: İrdelemeunclassified

Three Complicated Orf Cases

Şahin¹,

Namıduru²,

Karaoğlan³

2017

Klimik Dergisi

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Orf, a zoonosis transmitted from sheep and goat to human, is caused by Parapoxvirus. It is more common among occupational groups who are in close contact with animals. On the other hand after the feast of sacrifice or in spring and summer, it causes epidemic and threatens human health. It is mainly seen as papulonodular lesions on hands. Diagnosis is based on clinical findings, histological examination and viral DNA detection. However, it is usually diagnosed on the basis of exposure history and observation of characteristic lesions. Although it is rarely complicated, orf spontaneously recovers in general and does not require treatment. In this report, we presented three complicated orf cases demonstrating erythema multiforme, lymphangitis, and bullous pemphigoid. Klimik Dergisi 2017; 30(2): 90-2.

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“…The first case of Orf in humans was clinically manifested as solitary skin lesion in 1934 (277). In Turkey, the Orf virus infection has reemerged during the last two decades, and case reports and Orf outbreaks related to Orf in both animals and humans are available (278,279). The human case of Orf virus infection with a pyoderma-like lesion on the left indicator finger was diagnosed in a 37-year-old man in 2011 in Ankara, and the virus was molecularly characterized (280).…”

Section: Middle East Respiratory Syndrome Coronavirus (Mers-mentioning

confidence: 99%

Overview of Zoonotic Diseases in Turkey: The One Health Concept and Future Threats

İncı¹,

Doğanay²,

Özdarendeli³

et al. 2018

TurkiyeParazitolDerg

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Zoonotic infections are globally important diseases and lead to huge economic losses in both low-and middle-income and high-income countries. Global warming, environmental and ecological changes, illegal movement of animals and humans, regional civil wars, and poverty are predisposing factors for the emergence of zoonotic infections and their distribution worldwide; they are also a big threat for the future. In addition, environmental pollution and antimicrobial resistance are immense serious threats and dangers to prevent and control zoonotic infections. The natural location of Turkey allows many emerged or re-emerged infections with zoonotic characteristics by animal movements, such as bird immigrations, and by human movements due to civil wars as seen with regional refugees. Numerous zoonotic diseases, including 37 bacterial, 13 fungal, 29 viral, 28 parasitic (3 trematodes, 7 cestodes, 10 nematodes, and 8 protozoan), and totally 107 infections, have been reported from Turkey to date. Additionally, many ectoparasitic zoonoses within 15 different arthropod groups and one leech infestation have been reported from Turkey to date. The "One Health" initiative is particularly relevant for developing strategies to combat zoonotic diseases. In this article, we review the occurrence of zoonotic diseases in man and animals in Turkey in the light of the "One Health" perspective.

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Nosocomial outbreak of disseminated orf infection in a burn unit, Gaziantep, Turkey, October to December 2012

Cited by 32 publications

References 7 publications

Unique Presentation of Orf Virus Infection in a Thermal-Burn Patient After Receiving an Autologous Skin Graft

Unique Presentation of Orf Virus Infection in a Thermal-Burn Patient After Receiving an Autologous Skin Graft

Three Complicated Orf Cases

Overview of Zoonotic Diseases in Turkey: The One Health Concept and Future Threats

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