Nosocomial infections within the first month of solid organ transplantation

Dorschner, Peter B.; McElroy, Lisa M.; Ison, Michael G.

doi:10.1111/tid.12203

Cited by 70 publications

(86 citation statements)

References 130 publications

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“…The current scientific literature on SSIs associated with heart transplantation is limited, and the scientific literary output is focused on the incidence of SSIs in the transplanted population, that is, involving different types of transplants or, on studies on the incidence of infections in heart transplant patients, considering different sites on a single research 10 . In Brazil, only an article published in 2000, dealt specifically with SSIs among patients submitted to heart transplantation, however it only addressed mediastinitis 11 .…”

Section: Introductionmentioning

confidence: 99%

Surgical site infection in patients submitted to heart transplantation

Rodrigues

Ferretti-Rebustini

Poveda

2016

Rev. Latino-Am. Enfermagem

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Objectives: to analyze the occurrence and predisposing factors for surgical site infection in patients submitted to heart transplantation, evaluating the relationship between cases of infections and the variables related to the patient and the surgical procedure. Method: retrospective cohort study, with review of the medical records of patients older than 18 years submitted to heart transplantation. The correlation between variables was evaluated by using Fisher's exact test and Mann-Whitney-Wilcoxon test. Results: the sample consisted of 86 patients, predominantly men, with severe systemic disease, submitted to extensive preoperative hospitalizations. Signs of surgical site infection were observed in 9.3% of transplanted patients, with five (62.5%) superficial incisional, two (25%) deep and one (12.5%) case of organ/space infection. There was no statistically significant association between the variables related to the patient and the surgery. Conclusion: there was no association between the studied variables and the cases of surgical site infection, possibly due to the small number of cases of infection observed in the sample investigated.

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Section: Introductionmentioning

confidence: 99%

Surgical site infection in patients submitted to heart transplantation

Rodrigues

Ferretti-Rebustini

Poveda

2016

Rev. Latino-Am. Enfermagem

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“…22 Bacterial infections are most common and given the antibiotic exposure in the pre-and peritransplant period, multidrug-resistant organisms and Clostridium difficile have been increasingly implicated in recent years. 22 Bacterial infections are most common and given the antibiotic exposure in the pre-and peritransplant period, multidrug-resistant organisms and Clostridium difficile have been increasingly implicated in recent years.…”

Section: The Early Posttransplant Period (Month 0 To 1)mentioning

confidence: 99%

Infection in Renal Transplant Recipients

Sawinski¹,

Blumberg²

2019

Chronic Kidney Disease, Dialysis, and Transplantation

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“…Improvements in graft outcomes following solid organ transplantation have meant that the prevention of infection and its associated morbidity and mortality, has become a key focus in the care transplant recipients …”

Section: Introductionmentioning

confidence: 99%

A simple score can identify kidney transplant recipients at high risk of severe infection over the following 2 years

Dendle

Polkinghorne

Mulley

et al. 2019

Transplant Infectious Dis

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Background The aim of this study was to determine whether a composite score of simple immune biomarkers and clinical characteristics could predict severe infections in kidney transplant recipients. Methods We conducted a prospective study of 168 stable kidney transplant recipients who underwent measurement of lymphocyte subsets, immunoglobulins, and renal function at baseline and were followed up for 2 years for the development of any severe infections, defined as infection requiring hospitalization. A point score was developed to predict severe infection based on logistic regression analysis of factors in baseline testing. Results Fifty‐nine (35%) patients developed severe infection, 36 (21%) had two or more severe infections, and 3 (2%) died of infection. A group of 19 (11%) patients had the highest predicted infectious risk (>60%), as predicted by the score. Predictive variables were mycophenolate use, graft function, CD4+, and natural killer cell number. The level of immunosuppression score had an area under the receiver operating curve of 0.75 (95% CI: 0.67‐0.83). Conclusion Our level of immunosuppression score for predicting the development of severe infection over 2 years has sufficient prognostic accuracy for identification of high‐risk patients. This data can inform research that examines strategies to reduce the risks of infection.

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Nosocomial infections within the first month of solid organ transplantation

Cited by 70 publications

References 130 publications

Surgical site infection in patients submitted to heart transplantation

Surgical site infection in patients submitted to heart transplantation

Infection in Renal Transplant Recipients

A simple score can identify kidney transplant recipients at high risk of severe infection over the following 2 years

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