Nosocomial Infections in Hemodialysis Units

Tokars, Jerome I.; Alter, Miriam J.; Arduino, Matthew J.; Favero, Martin S.

doi:10.1016/b978-1-4160-0158-4.50025-2

Cited by 4 publications

(5 citation statements)

References 78 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Withdrawing the infected prosthetic or unused material (PTFE or catheter) should be considered as the best way of correcting inflammation [17] . AVG and TPC are known to be more prone to acute and chronic complications such as thrombosis and acute infection as compared to native AVF [18] . However, the influence of each kind of vascular access on the baseline micro-inflammatory status of HD patients in the absence of any clinical and/or laboratory evidence of acute or chronic infection has never been fully addressed.…”

Section: Discussionmentioning

confidence: 99%

The Kind of Vascular Access Influences the Baseline Inflammatory Status and Epoetin Response in Chronic Hemodialysis Patients

Movilli¹,

Brunori²,

Camerini³

et al. 2006

Blood Purif

View full text Add to dashboard Cite

Background: Arteriovenous grafts (AVG) and tunneled permanent catheters (TPC) are increasingly being used in hemodialysis (HD) patients. However, their role in baseline inflammatory status has not been fully evaluated. Aim of the study was to evaluate the influence of the current kind of vascular access on the baseline inflammatory status, marked by serum C-reactive protein (CRP), and the response to epoetin therapy in a group of iron-replete HD patients, under steady clinical conditions, without evidence of acute infections and/or inflammatory diseases. Methods: We studied 79 patients who had been on bicarbonate HD for 8–410 months and were receiving epoetin therapy. They all had adequate iron stores and stable hemoglobin (Hb) levels. Exclusion criteria were fever, signs of infection, white blood cell count (WBC) >10 × 1,000/µl, for at least 4 weeks before study. 48 patients (group A) had arteriovenous fistula (AVF), 18 patients (group B) AVG, 13 patients (group C) TPC. CRP, Hb, transferrin saturation, serum ferritin, WBC, serum albumin, protein catabolic rate, Kt/V, and epoetin dose (U/kg body weight/week) were measured. CRP values were log-transformed to normalize the distribution. Results: Log-transformed CRP values among the 3 groups were significantly different: group A 1.81 ± 0.48; group B 2.12 ± 0.50, and group C 3.00 ± 0.25 (group A vs. B p < 0.003; group B vs. C p < 0.001; group A vs. C p < 0.0001). CRP and the epoetin dose were directly correlated (r = 0.519; p < 0.0001). The epoetin doses among the 3 groups were significantly different. Multiple regression analysis confirmed AVG and TPC as factors independently influencing CRP levels. Conclusions: AVG and TPC have a higher degree of chronic inflammation than AVF. The epoetin requirement is increased in TPC and AVG compared with AVF.

show abstract

Section: Discussionmentioning

confidence: 99%

The Kind of Vascular Access Influences the Baseline Inflammatory Status and Epoetin Response in Chronic Hemodialysis Patients

Movilli¹,

Brunori²,

Camerini³

et al. 2006

Blood Purif

View full text Add to dashboard Cite

show abstract

“…Any microorganism that can grow in water can cause infections in hemodialysis patients. 1 C. indologenes is a gramnegative nonfermentative bacterium found in soil, water, and plants and is not part of the normal human flora. C. indologenes is a rare cause of disease in humans and has been implicated in bloodstream infections associated with implanted devices.…”

Section: Discussionmentioning

confidence: 99%

“…Pyrogenic reactions and bacteremia are important sequelae of hemodialysis and frequently ensue as a result of poor water quality or inadequate reprocessing of reusable dialyzers. 1 Bach Mai Hospital (BMH) is a 2,000-bed referral hospital in Hanoi, Vietnam, and houses the largest hemodialysis center in the country (>200 patients undergo hemodialysis each day). Infected dialysis-access sites and possible pyrogenic reactions are relatively common in this hemodialysis patient population and, on average, approximately 6 patients with fever and infected dialysis sites are admitted to the BMH acute medical services each week for further evaluation and treatment.…”

Section: Infect Control Hosp Epidemiol 2006; 27:424-426mentioning

confidence: 99%

Pyrogenic Reactions in Hemodialysis Patients, Hanoi, Vietnam

Archibald

Khoi

Jarvis

et al. 2006

Infect. Control Hosp. Epidemiol.

View full text Add to dashboard Cite

Of 33,111 patients admitted to a large hospital in Vietnam from November 2000 through July 2001, a total of 303 were undergoing hemodialysis and had pyrogenic reactions (ie, fever and/or rigors). Ten case patients (3.3%) had documented bacteremia; pathogens were largely waterborne microorganisms. Pyrogenic reactions in case patients might have occurred because of suboptimal water quality or inadequate dialyzer reprocessing procedures.

show abstract

“…Identification and prevention of catheter-related complications is a critical point to improve hemodialysis patient care (Shah et al, 2013). Infection, is the second most common cause of mortality in human dialysis patients, accounting for 14% of deaths, with the majority of infections being catheter related (28-33% in one study) (Evers, 1995;Tokars et al, 2005;Katneni and Hedayati, 2007). In one study, bacterial infection is responsible for more than 30% of all cause morbidity and mortality in human patients, with vascular access infection being the culprit in 73% of all bacteremias (Langston, 2011).…”

Section: Introductionmentioning

confidence: 99%

“…In one study, bacterial infection is responsible for more than 30% of all cause morbidity and mortality in human patients, with vascular access infection being the culprit in 73% of all bacteremias (Langston, 2011). In human medicine bacteremia occurs in 0.6-1.7% of human dialysis patients per month, with vascular access infections occurring in 1.3-7.2% of patients (Tokars et al, 2005).…”

Section: Introductionmentioning

confidence: 99%

Bacterial colonization of non-permanent central venous catheters in hemodialysis dogs

Perondi

Petrescu

Fratini

et al. 2020

Heliyon

View full text Add to dashboard Cite

Non-permanent central venous catheters (CVCs), are the most commonly used vascular access in veterinary patients undergoing hemodialysis. In human dialysis patients, CVC infection represents a common cause of morbidity and mortality. The aim of this retrospective observational study was to evaluate the prevalence of bacterial colonization of CVCs in dogs submitted to hemodialysis treatment at time of CVC removal.The CVCs of all dogs submitted to hemodialysis (n ¼ 23) at the Veterinary Teaching Hospital ''Mario Modenato'' of the University of Pisa between January 2015 and December 2016 were considered. For all dogs, data regarding signalment, reason for hemodialysis treatment, duration of catheterization ( 15 or >15 days), CVC complications, and 30-day survival were considered. Statistical analysis was performed using Graph Pad Prism™. Five over 23 dogs (22%) showed positive bacterial culture of CVC (þ), and 18/23 dogs (78%) negative culture of CVC (-). The most prevalent microorganism was Staphylococcus Spp (3/5; 60%). No significant difference was found in the prevalence of CVC infection according to age, gender, reason for hemodialysis, CVC complications, duration of catheterization, and outcome. No statistically significant difference (p ¼ 0.64) in survival curves was reported at log rank analysis between dogs with CVC -and CVC þ.The prevalence of bacterial CVC contamination in our dialysis dogs showed relatively low. Exclusive use of CVC for hemodialysis, good hygiene practice during CVC management, and use of chlorhexidine as an antiseptic should be strongly encouraged.

show abstract

Nosocomial Infections in Hemodialysis Units

Cited by 4 publications

References 78 publications

The Kind of Vascular Access Influences the Baseline Inflammatory Status and Epoetin Response in Chronic Hemodialysis Patients

The Kind of Vascular Access Influences the Baseline Inflammatory Status and Epoetin Response in Chronic Hemodialysis Patients

Pyrogenic Reactions in Hemodialysis Patients, Hanoi, Vietnam

Bacterial colonization of non-permanent central venous catheters in hemodialysis dogs

Contact Info

Product

Resources

About