Nosocomial Infections at Three Regional Tertiary Hospitals in Trinidad and Tobago

Elliott, C. G.; Justiz-Vaillant, A

doi:10.31579/2692-9406/001

Cited by 2 publications

(1 citation statement)

References 54 publications

(65 reference statements)

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“…Risk factors, antibiotic resistance patterns, and management strategies for these infections are also discussed. Overall, the review highlights the significant burden of nosocomial infections and the importance of implementing effective preventive measures and management protocols to mitigate their impact on patient outcomes and healthcare systems [81] .…”

Section: Nosocomial Infections In Trinidad and Tobagomentioning

confidence: 99%

Advancements in Immunology and Microbiology Research: A Comprehensive Exploration of Key Areas and Global Impact

Justiz-Vaillant,

Gopaul,

Soodeen

et al. 2024

Preprint

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Immunology and microbiology research in the West Indies has witnessed remarkable growth and innovation, playing a pivotal role in advancing our understanding of immune mechanisms, disease pathogenesis, and therapeutic interventions. This manuscript presents a comprehensive exploration of key areas in West Indian immunology research, spanning from the utilization of bacterial proteins as antibody reagents to the intricate realms of clinical immunology and disease management. The utilization of bacterial immunoglobulin-binding proteins (IBPs), including protein A (SpA), protein G (SpG), and protein L (SpL), has revolutionised serological diagnostics in the region. promise in early disease detection and precision medicine. Microbiological studies in the Caribbean region have shed light on antimicrobial resistance patterns, particularly the emergence of extended-spectrum beta-lactamases (ESBLs), guiding antimicrobial stewardship programs and informing therapeutic strategies. Clinical immunology research has elucidated the molecular pathways underlying immune-mediated disorders, leading to tailored management strategies for conditions such as severe combined immunodeficiency (SCID), neuropsychiatric lupus erythematosus (NPLE), and others. In summary, West Indian immunology and microbiology research has made significant contributions to global healthcare, fostering collaboration, innovation, and improved patient outcomes.

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Section: Nosocomial Infections In Trinidad and Tobagomentioning

confidence: 99%

Advancements in Immunology and Microbiology Research: A Comprehensive Exploration of Key Areas and Global Impact

Justiz-Vaillant,

Gopaul,

Soodeen

et al. 2024

Preprint

View full text Add to dashboard Cite

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Incidence and determinants of nosocomial infection among hospital admitted adult chronic disease patients in University of Gondar Comprehensive Specialized Hospital, North–West Ethiopia, 2016–2020

Taye¹,

Abebil

Akalu

et al. 2023

Front. Public Health

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BackgroundNosocomial infections are major public health problem which affects more than 100 million patients each year globally. This leads to prolonged hospital stays, a high mortality rate, and a vast financial burden to the healthcare system as well as the patients. This study aimed to find out the incidence of nosocomial infections and determinant factors among admitted adult chronic illness patients at the University of Gondar Comprehensive Specialized Hospital, Northwest Ethiopia.MethodsAn institutional-based retrospective follow-up study design was employed among 597 respondents. The secondary data was collected from April 15 to May 15, 2021. A computer-generated random sampling technique was used to select a total of 599 patients using Open-epi software. Structured checklists were used to collect data. For data entry and analysis Epi-Data version 4.6 and STATA 16 were used respectively. To identify statistically significant variables Cox-regressions (univariable and multivariable) were performed. To declare statistically significant variables based on p < 0.05 in the multivariable Cox-regression model, adjusted hazard ratio with 95% CI was used.ResultsA total of 597(99.6%) adult chronic illness patients were included in the study. Of these, 53 (8.88%) participants developed nosocomial infections and the incidence rate of nosocomial infection was 6.6 per 1,000 person-days observation. In this study, not taking antibiotics (AHR = 2.74, 95% CI: 1.49, 5.04), using mechanical ventilation (AHR = 2.67, 95% CI: 1.36, 5.26), being on urinary catheter (AHR = 4.62, 95% CI: 2.22, 9.65), being on intravenous catheter (AHR = 3.42, 95% CI: 1.22, 9.61) and length of hospital stay >20 days (AHR = 2.66, 95% CI: 1.43, 4.94) were significantly associated with nosocomial infections.ConclusionsThe findings have indicated that the incidence of nosocomial infection was low. No taking antibiotics, intravenous insertion, mechanical ventilation, length of hospital stay, and urinary catheterization were the predictors for the development of nosocomial infection. Therefore, we recommend that the healthcare providers need to give emphasis on infection prevention and control in the institution on these factors that have a significant effect on nosocomial infection.

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Nosocomial Infections at Three Regional Tertiary Hospitals in Trinidad and Tobago

Cited by 2 publications

References 54 publications

Advancements in Immunology and Microbiology Research: A Comprehensive Exploration of Key Areas and Global Impact

Advancements in Immunology and Microbiology Research: A Comprehensive Exploration of Key Areas and Global Impact

Incidence and determinants of nosocomial infection among hospital admitted adult chronic disease patients in University of Gondar Comprehensive Specialized Hospital, North–West Ethiopia, 2016–2020

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