2010
DOI: 10.1016/j.nmd.2010.06.014
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North Star Ambulatory Assessment, 6-minute walk test and timed items in ambulant boys with Duchenne muscular dystrophy

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Cited by 177 publications
(171 citation statements)
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References 24 publications
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“…All patients in the 2 investigator‐initiated studies (historical control group) had a genetically confirmed diagnosis of DMD and met predefined entry criteria 25, 30. All eligible patients visiting the participating centers during the enrollment period were enrolled, supporting that the population analyzed represented an appropriate and unbiased control cohort of DMD patients.…”
Section: Methodsmentioning
confidence: 96%
See 1 more Smart Citation
“…All patients in the 2 investigator‐initiated studies (historical control group) had a genetically confirmed diagnosis of DMD and met predefined entry criteria 25, 30. All eligible patients visiting the participating centers during the enrollment period were enrolled, supporting that the population analyzed represented an appropriate and unbiased control cohort of DMD patients.…”
Section: Methodsmentioning
confidence: 96%
“…These 2 investigator‐initiated studies are the only DMD natural history data sets that have prospectively and consistently collected 6MWT assessments for a substantial number of patients for 36 months or longer. Comparability to the eteplirsen data set is supported by equivalent requirements across the studies for genetic confirmation of DMD diagnosis, patient care according to the same international treatment guidelines for DMD,27, 28 6MWT administration following generally accepted standards,13, 29, 30 and exclusion of patients with cognitive impairment that could interfere with test adherence. Patient‐level data from the registries were pooled, and analysis was performed to evaluate impact of genotype on disease natural history as well as to compare an appropriately matched historical control group to eteplirsen‐treated patients.…”
mentioning
confidence: 99%
“…O presente estudo buscou um teste validado e de fácil aplicabilidade, pois diversos autores relatam que esta é uma ferramenta de fácil aplicabilidade e acessível que pode ser facilmente utilizada em meninos com DMD deambulador sem comprometimento cognitivo ou problemas comportamentais 17 . Além destes fatores, observamos a necessidade de incrementar o teste com comando verbal contínuo, a fim de estimular a deambulação durante os testes em solo e em água.…”
Section: Discussionunclassified
“…Observamos que apesar do empuxo facilitar a flexão de quadril e joelhos durante a fase de balanço, o contrário ocorreu na fase de apoio, onde é necessario aumentar a demanda energética para vencer o empuxo e apoiar o membro para realizar o deslocamento. Devido à combinação da perda da resistência e do envolvimento cardiopulmonar, os pacientes com DMD têm um aumento no gasto energético durante a locomoção (mais energia metabólica consumida por distância percorrida) com o aumento da progressão da doença 17 .…”
Section: Discussionunclassified
“…The "Spinal Muscle Atrophy Functional Motor Scale" was prepared for SMA patients [118], the "Amyotrophic Lateral Sclerosis Functional Classification Scale" and the ALS score for patients with ALS [82], and the "Hammersmith Motor Skill Score" for patients with DMD [119]. Among the scales focusing only on one region/function of the body, Trunk Control Test and Trunk Impairment Scale are for the trunk [120,121], the "Brooke Upper Extremity Scale" is for upper extremity [122], the "Vignos Lower Extremity Scale" is for lower extremity [123], the "North Star Ambulatory Assessment" is for ambulation [124] and the "Jebsen-Taylor Hand Function Test" and "Activlim" are for the hand functions [125,126].…”
Section: Assessment Of Motor Functionmentioning
confidence: 99%