Neuromuscular Diseases and Rehabilitation

Demir, Yusuf

doi:10.5772/67722

Cited by 4 publications

(4 citation statements)

References 169 publications

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“…Adults with neuromuscular disorders (NMD), including slowly-progressive neuromuscular diseases and peripheral nervous system injuries, often experience walking limitations [ 1 ] caused by a loss of lower extremity muscle strength [ 2 ]. Walking limitations typically include increased walking energy cost [ 3 , 4 ], diminished walking speed [ 3 , 5 ], pain [ 6 ], reduced balance and increased fall risk [ 7 , 8 ], which together hinder daily physical activity [ 9 ] and negatively impact quality of life [ 10 ].…”

Section: Introductionmentioning

confidence: 99%

Effects of specialist care lower limb orthoses on personal goal attainment and walking ability in adults with neuromuscular disorders

et al. 2023

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Background Lower limb orthoses intend to improve walking in adults with neuromuscular disorders (NMD). Yet, reported group effects of lower limb orthoses on treatment outcomes have generally been small and heterogeneous. We propose that guideline-based orthotic care within a multidisciplinary expert setting may improve treatment outcomes. Aim To examine the effectiveness of specialist care orthoses compared to usual care orthoses on personal goal attainment and walking ability. Design Cohort study. Population Adults with NMD who experienced walking problems due to calf and/or quadriceps muscle weakness and were provided with a specialist care lower limb orthosis between October 2011 and January 2021. Methods Three months after provision, the specialist care orthosis was compared to the usual care orthosis worn at baseline in terms of personal goal attainment (Goal Attainment Scaling (GAS)), comfortable walking speed (m/s), net energy cost (J/kg/m) (both assessed during a 6-minute walk test), perceived walking ability and satisfaction. Results Sixty-four adults with NMD were eligible for analysis. The specialist care orthoses comprised 19 dorsiflexion-restricting ankle-foot orthoses (AFOs), 22 stance-control knee-ankle-foot orthoses (KAFOs) and 23 locked KAFOs. Overall, 61% of subjects showed a clinically relevant improvement in GAS score. Perceived safety, stability, intensity, fear of falling and satisfaction while walking all improved (p≤0.002), and subjects were satisfied with their specialist care orthosis and the services provided. Although no effects on walking speed or net energy cost were found in combined orthosis groups, specialist care AFOs significantly reduced net energy cost (by 9.5%) compared to usual care orthoses (from mean (SD) 3.81 (0.97) to 3.45 (0.80) J/kg/m, p = 0.004). Conclusion Guideline-based orthotic care within a multidisciplinary expertise setting could improve treatment outcomes in adults with NMD compared to usual orthotic care by improvements in goal attainment and walking ability. A randomized controlled trial is now warranted to confirm these results.

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Section: Introductionmentioning

confidence: 99%

Effects of specialist care lower limb orthoses on personal goal attainment and walking ability in adults with neuromuscular disorders

et al. 2023

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“…Neuromuscular diseases (NMDs) are a heterogeneous group of diseases that affect skeletal muscles. Abnormalities in the anterior horn motor cells, peripheral nerves, neuromuscular junctions, or muscles can lead to inherited or acquired NMDs [ 1 , 2 ]. Spinal Muscular Atrophy (SMA) and Duchenne Muscular Dystrophy (DMD) are the most common neuromuscular diseases that affect children [ 1 , 3 , 4 ].…”

Section: Introductionmentioning

confidence: 99%

Translation and validation of Indonesian version of Pediatric Quality of Life Inventory™ (PedsQL™) Neuromuscular Module

Wiwaha

Sari

Biben

et al. 2022

Health Qual Life Outcomes

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Background The Pediatric Quality of Life™ 3.0 Neuromuscular Module is an instrument to assess health-related quality of life (HRQoL) among children with neuromuscular diseases (NMDs) aged 2–18 years. This study aimed to determine whether the PedsQL™ 3.0 Neuromuscular Module Indonesian Version is valid and reliable. Methods This study used the Indonesian translation of the PedsQL™ 3.0 Neuromuscular Module after getting formal permission from the inventor, and the translation process followed the Mapi linguistic translation guidelines. This study administered the PedsQL™ 3.0 Neuromuscular Module Indonesian Version to 84 parents and 71 children. In addition, we used the Rasch model to analyze the psychometric properties. Results The reliability of the total scale of the PedsQL™ Neuromuscular Module Indonesian Version shows good to very good criteria. On the parent proxy-report, Cronbach alpha was 0.95, person reliability was 0.84, item reliability was 0.93, person separation was 2.32, item separation was 3.61, person strata separation was 4 levels, and item strata separation was 5 levels. On the child self-report, Cronbach alpha was 0.93, person reliability was 0.81, item reliability was 0.81, person separation was 2.08, item separation was 2.06, person strata separation was 3 levels, and item strata separation was 3 levels. The total scale of the PedsQL Neuromuscular Module Indonesian Version shows fair to good construct validity in parent proxy-report (explained variance 51.9%; unexplained variance 8.4%) and child self-report (explained variance 40.9%; unexplained variance 12.6%). There were no misfit items in the parent proxy-report (infit 0.66–1.49; outfit 0.51–1.81; point measure correlation 0.36–0.93) and child self-report (infit 0.53–1.65; outfit 0.50–1.73; point measure correlation 0.31–0.90) identified by the Rasch models. Conclusions The PedsQL™ 3.0 Neuromuscular Modul Indonesian Version is a valid and reliable instrument in measuring HRQoL in Indonesian children with neuromuscular diseases.

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“…Neuromuscular disorders are often incurable and result in lack of motor control over time [1]. Physical therapy is currently recognized as the primary movement rehabilitation option for regaining strength, treating symptoms, enhancing quality of life, delaying disease progression, and restoring independent function [2]. However, physical therapy is limited as such treatment neglects consideration for neurocognitive contributions of motor learning towards recovery.…”

Section: Introductionmentioning

confidence: 99%

Instrumented Upper-Body Brace for Computerized Training of Muscle Control

Vataksi¹,

Sanford²,

Liu³

et al. 2022

World Congress on Electrical Engineering and Computer Systems and Science

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Each year in the United States, over 2,000,000 individuals suffer from neuromuscular disorders that severely impair movement abilities. Physical therapy is the predominant option for rehabilitating motor function for these patients; however, traditional therapies often focus on physical training without greater cognitive engagement or leveraging of motor learning principles. As such, computerized interfaces for rehabilitation, such as virtual reality and robotics, are more promising given their natural approaches to motivate and provide enhanced feedback about performance while re-training motor skills. Our laboratory has prototyped an upperextremity brace device integrated with a virtual reality environment for isometric training of improved muscle-level control of the upperbody for persons with motor disability. This research platform includes a position-adjustable restrictive upper-extremity brace instrumented with sensors for skin-surface electromyography (EMG, measure muscle activity) to control virtual avatars and vibration motors for haptic guidance cues during training. The core objective of this research is to adapt the current brace design to better include instrumentation elements (EMG sensors, vibration motors) onboard the brace towards an embodiment of this device that is self-contained and with greater commercial potential. Specifically, this project will focus on building the next version of this brace system that allows for custom-placement of affordable (not high-end research-grade) commercial EMG (Myoware) sensors at locations personally fitted to each participant. The Myoware sensors will be embedded onto the current upper-body restrictive brace through modular attachments based on designs developed in SolidWorks as presented in this paper. The SolidWorks design utilizes sliding mechanisms, screws, springs, and clamps to make the modular attachment more user-friendly and position adaptable in three dimensions. Embedding Myoware sensors onto the brace design replaces the need to tape research-grade (Delsys) sensors onto each participant to ensure flush and consistent contact with each participant arm for robust EMG measurements and reliable transfer of haptic feedback. Overall, these improved design implementations will result in a version of this device that is more affordable, easier to use, more customizable to each user, and facilitates greater portability. The potential customers and stakeholders would include not only patients, but also clinical support staff and telehealth companies. This versatile, advanced system for computerized rehabilitation will be valuable to any communities of neuromuscular disorders affecting upper-body function that benefit from motor rehabilitation.

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Neuromuscular Diseases and Rehabilitation

Cited by 4 publications

References 169 publications

Effects of specialist care lower limb orthoses on personal goal attainment and walking ability in adults with neuromuscular disorders

Effects of specialist care lower limb orthoses on personal goal attainment and walking ability in adults with neuromuscular disorders

Translation and validation of Indonesian version of Pediatric Quality of Life Inventory™ (PedsQL™) Neuromuscular Module

Instrumented Upper-Body Brace for Computerized Training of Muscle Control

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