North American Solitaire Stent Retriever Acute Stroke registry: post-marketing revascularization and clinical outcome results

Abstract

The NASA registry demonstrated that the Solitaire FR device performance in clinical practice is comparable with the SWIFT and TREVO 2 trial results.

North American SOLITAIRE Stent-Retriever Acute Stroke Registry

“…As in the NASA Registry, there was no increase in sICH. 9 The reason(s) for the differential effects of LA versus GA are not known. There are theoretical concerns of neurotoxicity of certain anesthetic agents, but other agents may be neuroprotective, and specific data on the type of anesthetic used in the GA patients in this study are unavailable.…”

“…9 This device has been associated with rapid recanalization and low rates of intracranial hemorrhage (ICH) compared with the Merci Retriever (Stryker Neurovascular Inc, Fremont, CA) raising the possibility that its use may attenuate the apparent deleterious effects of GA. 3 In this substudy, data on anesthesia modality were reviewed to determine whether use of the Solitaire FR device was also associated with worse outcomes in patients treated under GA.…”

Comparison of Modern Stroke Thrombectomy Approaches Using an In Vitro Cerebrovascular Occlusion Model

“…1,2 Postmarketing experience indicates that in modern clinical practice, Stentrievers are often used in conjunction with another device such as an aspiration thrombectomy catheter or a balloon-guide catheter. [3][4][5] Moreover, direct aspiration thrombectomy by using recently developed large-bore aspiration catheters has shown promise as an effective alternative approach for intra-arterial revascularization. 6,7 However, the recanalization effectiveness of these types of thrombectomy devices has not been compared in a randomized trial, to our knowledge.…”

The Curved MCA: Influence of Vessel Anatomy on Recanalization Results of Mechanical Thrombectomy after Acute Ischemic Stroke

“…1 While studies suggest that intravenous thrombolysis by using recombinant tissue plasminogen activator is barely effective in large-vessel occlusions, [2][3][4] recent studies have shown that endovascular mechanical thrombectomy (MT) by using second-generation devices, known as stent retrievers, is associated with high recanalization rates and substantially improved clinical outcome. [5][6][7][8][9][10][11] However, in approximately 10%-25% of the patients, a successful recanalization (TICI 2b/3) still cannot be achieved. [5][6][7][8][9][10][11][12][13][14] Only a couple of technical factors are understood that may determine the fate of these patients: First, histologic characteristics of thromboemboli may influence recanalization results.…”

“…[5][6][7][8][9][10][11] However, in approximately 10%-25% of the patients, a successful recanalization (TICI 2b/3) still cannot be achieved. [5][6][7][8][9][10][11][12][13][14] Only a couple of technical factors are understood that may determine the fate of these patients: First, histologic characteristics of thromboemboli may influence recanalization results. 15 Second, thrombus length has been identified as a relevant factor.…”