Objective
To determine the benefits associated with brief inpatient rehabilitation for Covid-19 patients.
Design
Retrospective chart review.
Setting
A newly created specialized rehabilitation unit in a tertiary care medical center
Participants
Consecutive sample of the first 100 patients with Covid-19 infection admitted to rehabilitation.
Intervention
Inpatient rehabilitation for post-acute care Covid-19 patients
Main Outcome Measures
Measurements, at admission and discharge, comprised a Barthel Activities of Daily Living Index (including baseline value before Covid-19 infection), time to perform 10 sit-to-stands with associated cardio-respiratory changes, and grip strength (dynamometry). Correlations between these outcomes and the time spent in ICU were explored.
Results
Patient characteristics upon admission to rehabilitation were: men 66%, age 66±22 years, mean delay from symptom onset 20.4±10.0 days, BMI 26.0±5.4 kg/m
2
, hypertension 49%, diabetes 29%, with 26% having >50% pulmonary damage on CT-scans. Mean length of rehabilitation stay was 9.8±5.6 days. From admission to discharge, the Barthel index (/100) increased from 77.3±26.7 to 88.8±24.5 (
p
<0.001), without recovering baseline values (94.5±16.2;
p
<0.001). There was a 37% improvement in sit-to-stand frequency (0.27±0.16 to 0.37±0.16 Hz;
p
<0.001), a 13% decrease in post-test respiratory rate (30.7±12.6 to 26.6±6.1;
p
=0.03), and a 15% increase in grip strength (18.1±9.2 to 20.9±8.9 kg;
p
<0.001). At both admission and discharge, Barthel score correlated with grip strength (rho=0.39-0.66;
p
<0.01), which negatively correlated with time spent in ICU (rho=-0.57 to -0.49,
p
<0.05).
Conclusions
Inpatient rehabilitation for Covid-19 patients was associated with substantial motor, respiratory and functional improvement, especially in severe cases, even though there remained mild persistent autonomy loss upon discharge. Following acute stages, Covid-19, primarily a respiratory disease, might convert into a motor impairment correlated with the time spent in intensive care.