Normal Values and Incidence of Cardiorespiratory Complications in Dogs During General Anaesthesia. A Review of 1281 Cases

Redondo, J. I.; Rubio, Mónica; Soler, G.; Serra, I; Soler, Carlos; Gómez-Villamandos, R.J.

doi:10.1111/j.1439-0442.2007.00987.x

Cited by 86 publications

(86 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…For control dogs, the heart rate varied from 73 to 118 bpm, values below the normal range for dogs (70 to 140 bpm). Animals of the poisoned group had a heart rate ranging from 42 to 181 bpm (18). These values had a wide variation; four animals had bradycardia (26%), seven had tachycardia (46%) and four had values within the normal range.…”

Section: Resultsmentioning

confidence: 99%

“…When times were compared, the AP increase was also significant at 20 minutes for systolic and mean values, which is due to the venom causing a gradual AP increase and values keeping above normality at 30 minutes after the venom administration (3,9). After this time, AP (systolic, diastolic and mean) values were above the normal values for dogs (18).…”

Section: Discussionmentioning

confidence: 99%

“…However, the catecholamines present in the venom may overcome this effect, which explains the possible occurrence of both sinus bradycardia and tachycardia (17 (18).…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Clinical and electrocardiographic evaluation during experimental toad poisoning in dogs

Camplesi¹,

Sakate²,

Simão³

et al. 2010

J. Venom. Anim. Toxins incl. Trop. Dis

View full text Add to dashboard Cite

Accidents involving toad poisoning are frequent and dogs are the most common victims; they become poisoned by biting or ingesting a toad. When released in the organism, the venom is absorbed by both the oral mucosa and the digestive tract, initiating its toxic action. The aim of this work was to evaluate the clinical and electrocardiographic aspects of dogs subjected to experimental toad poisoning, as well as their response to treatment with propranolol. Twenty dogs were divided into two groups, a control group (n = 5) and a poisoned group (n = 15). After general anesthesia, the control group received a placebo, while the poisoned group received a venom aliquot through an orogastric tube. Results were tested through multivariate analysis (p < 0.05). The animals in the poisoned group had gastrointestinal symptoms including emesis, intense salivation, hyperemic or congested oral mucosa and pasty diarrhea. Non-responsive mydriasis, nystagmus, depression, stupor, tachypnea, opisthotonus and ataxia were also manifested by 100% of the poisoned animals. Affected dogs had an increase in blood pressure, statistically significant throughout study. Five poisoned animals developed ventricular tachycardia and were treated with propranolol (0.5 mg/kg IV). All propranolol-treated animals returned to normal sinus rhythm, which evidences the efficacy of this drug to treat ventricular arrhythmias caused by toad venom.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Clinical and electrocardiographic evaluation during experimental toad poisoning in dogs

Camplesi¹,

Sakate²,

Simão³

et al. 2010

J. Venom. Anim. Toxins incl. Trop. Dis

View full text Add to dashboard Cite

show abstract

“…A decrease in average values for blood pressure (systolic, diastolic, and mean) and heart rate in dogs during anesthesia has been described in a large-scale meta-analysis (Redondo et al, 2007). In this study, propofol was used for induction in 1040 out of a total of 1281 studied cases.…”

mentioning

confidence: 93%

Evaluation of Adeno-Associated Viral Vectors for Liver-Directed Gene Transfer in Dogs

et al. 2011

View full text Add to dashboard Cite

This study evaluated six adeno-associated viral (AAV) vectors expressing green fluorescent protein (GFP) from the liver-specific thyroid hormone-binding globulin (TBG) promoter made with novel capsids in canine liverdirected gene transfer. Studies in 1.5-month-old dogs, which were administered vector through a peripheral vein, showed that AAV8 capsid vectors had the most favorable performance profiles. Interestingly, the absolute levels of hepatocyte transduction achieved with AAV8 were lower in dogs compared with what had been achieved in mice and nonhuman primates. Additional studies were performed with AAV8 delivered into the hepatic artery in adult dogs, with higher doses of vector used to assess potential dose-limiting toxicities. These studies showed good transduction on day 7 in one dog that apparently was lost by day 28 in another dog through the generation of GFP-specific T cells. Each adult dog was carefully monitored for any hemodynamic changes associated with vector infusion. Both animals demonstrated mild to moderate hypotension and bradycardia, which appeared to be anesthesia-related, making it difficult to evaluate contributions of the vector.

show abstract

“…Dessa forma, com base nas variações da f, pode-se afirmar que o uso do propofol associado ao butorfanol potencializou o efeito depressor do anestésico geral sobre o sistema respiratório (5) ; no entanto, estudos relativos à ventilometria envolvendo a associação enriqueceriam os achados e trariam maior embasamento a esta hipótese. A SpO 2 permaneceu dentro do intervalo de normalidade, indicando que a ventilação controlada com fração inspirada de oxigênio de 60% manteve satisfatório o grau de oxigenação tissular (20) . A utilização do butorfanol associado à acepromazina inferiu resultado semelhante em cães mantidos sob ventilação espontânea; no entanto, foi necessário o uso de FiO 2 de 100% para manter níveis adequados de SpO 2 (9) .…”

Section: Resultsunclassified

Efeitos Hemodinâmicos Da Infusão Contínua De Butorfanol Em Cães Anestesiados Com Propofol

et al. 2015

View full text Add to dashboard Cite

ResumoObjetivou-se avaliar os efeitos hemodinâmicos decorrentes da anestesia total intravenosa com propofol e butorfanol em cães. Para tal, foram utilizados 20 animais adultos hígidos, sem raça definida, distribuídos em dois grupos, designados como GB e GP, induzidos à anestesia com propofol (10 mg/kg). Após a intubação orotraqueal, instituiu-se ventilação controlada com oxigênio a 60% e fluxo de 30 mL/kg/min em circuito fechado, com volume controlado. A manutenção anestésica foi realizada com a administração de 0,6 mg/kg/min de propofol. O grupo butorfanol (GB) recebeu butorfanol 0,1 mg/kg IV, seguido de infusão contínua (40 µg/kg/h). O grupo placebo (GP) recebeu somente NaCl 0,9% em bolus, seguido de infusão venosa, em volume idêntico ao do GB. As variáveis hemodinâmicas foram avaliadas antes da aplicação do opioide ou da solução de NaCl a 0,9% (M0) e imediatamente após, em intervalos de 15 minutos (M15 a M75). A administração de butorfanol resultou em redução da resistência periférica total (RPT), das pressões arteriais (PAS, PAD e PAM) e do débito cardíaco (DC), sem relevância clínica. Os resultados permitem concluir que a associação proporciona anestesia segura para pacientes com suporte ventilatório. Palavras-Chave: anestesia total intravenosa; monitoramento; opioide. AbstractThe aim of this study was to evaluate the hemodynamic effects of the total intravenous anesthesia with propofol and butorphanol in dogs. For that purpose, twenty adult healthy crossbred dogs were used. The animals were equally allocated into two groups (PG and BG) and induced to the anesthesia with intravenous propofol (10 mg/kg). After orotracheal intubation, controlled ventilation was instituted with 60% oxygen and flow of 30 mL/kg/min in a closed system, with controlled volume. The anesthetic maintenance was accomplished with propofol (0.6 mg/kg/min). The butorphanol group (BG) received, butorphanol 0.1 mg/kg IV, followed by continuous infusion (40 µg/kg/h). The placebo group (PG) received only NaCl 0.9% in bolus, followed by venous infusion, in identical volume of

show abstract

Normal Values and Incidence of Cardiorespiratory Complications in Dogs During General Anaesthesia. A Review of 1281 Cases

Cited by 86 publications

References 18 publications

Clinical and electrocardiographic evaluation during experimental toad poisoning in dogs

Clinical and electrocardiographic evaluation during experimental toad poisoning in dogs

Evaluation of Adeno-Associated Viral Vectors for Liver-Directed Gene Transfer in Dogs

Efeitos Hemodinâmicos Da Infusão Contínua De Butorfanol Em Cães Anestesiados Com Propofol

Contact Info

Product

Resources

About