Normal Renal Blood Flow Measurement Using Phase-Contrast Cine Magnetic Resonance Imaging

Sommer, Graham; Noorbehesht, B.; Pelc, Norbert J.; Jamison, Rex L.; Pinevich, A. J.; Newton, Lynne; Myers, Bryan D.

doi:10.1097/00004424-199206000-00012

Cited by 41 publications

(23 citation statements)

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“…The obtained absolute flow measurements in the renal arteries and abdominal aorta correspond well with results of other published studies [20,21,22,23,24].…”

Section: Discussionsupporting

confidence: 89%

“…Several published reports show reliable flow measurements using MR techniques without respiratory synchronization [19,21,24,25], whereas others identify respiratory motion as a significant potential source of error in quantitative flow assessment in the renal arteries [20,22,23]. This contrast could be related to differences in the location of the parasagittal imaging plane with respect to the aorta, since respiration is likely to have a more significant influence on motion of the renal vessels in the periphery than in their central segment.…”

Section: Discussionmentioning

confidence: 99%

“…In the past few years, several phase-contrast MR techniques have been proposed for quantification of blood flow in the renal arteries [19,20]. However, the reported results show varying success in renal blood flow measurement compared with results obtained by means of para-aminohippurate (PAH) clearance.…”

Section: Introductionmentioning

confidence: 99%

“…However, the reported results show varying success in renal blood flow measurement compared with results obtained by means of para-aminohippurate (PAH) clearance. Respiratory motion, which causes the renal arteries to move during data acquisition, appears to be a considerable source of error in these measurements [20,21,22]. Synchronization with respect to respiratory motion, along with cardiac triggering, seems to be necessary to obtain accurate, reproducible flow data [22,23].…”

Section: Introductionmentioning

confidence: 99%

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Renal artery blood flow: quantification with breath-hold or respiratory triggered phase-contrast MR imaging

et al. 2000

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The aim of this study was to evaluate the validity and reproducibility of breath-hold and respiratory triggered phase-contrast (PC) MR imaging techniques in the measurement of renal artery blood flow. In 12 healthy subjects cardiac-gated PC flow measurements were obtained in the renal arteries using a breath-hold and a respiratory-triggered technique. The flow measurements were repeated in each renal artery separately. Comparison between the sum of flow measurements in the renal arteries and the difference in aortic flow measurements above and below the renal arteries served as an internal control. The flow measurements showed a good reproducibility both with the breath-hold (r=0.92, p < 0.0001) and with the respiratory-triggered (r = 0.91, p < 0.0001) technique. The validity of both methods was good and there was no statistically significant difference. Reproducible quantitative measurements of renal artery blood flow are possible with respiratory controlled, cardiac-gated, PC MR imaging.

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“…The obtained absolute flow measurements in the renal arteries and abdominal aorta correspond well with results of other published studies [20,21,22,23,24].…”

Section: Discussionsupporting

confidence: 89%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Renal artery blood flow: quantification with breath-hold or respiratory triggered phase-contrast MR imaging

et al. 2000

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“…It is important to emphasize that voxels that include the vessel wall will not contribute to the flow estimate, because the velocity in those voxels should equal zero or average to zero. The standard deviations of the repeated flow measurements obtained in five patients of this study, average 11.5%, range 0.53-18.2%, were slightly higher than but comparable with the 5-10% standard deviation reported in the literature for flow measurements of the renal artery and other medium sized vessels (31,32).…”

Section: Discussionsupporting

confidence: 86%

MR determination of glomerular filtration rate in subjects with solitary kidneys in comparison to clinical standards of renal function: feasibility and preliminary report

Katzberg

Buonocore

Low

et al. 2009

Contrast Media & Molecular

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This study was conducted to demonstrate the feasibility of quantifying single kidney glomerular filtration rate (skGFR) by magnetic resonance (MR) by comparison to the clinical estimates of GFR in volunteer subjects with a single kidney. Seven IRB-approved subjects with a solitary kidney, stable serum creatinine (SCr) and a 24 h creatinine clearance (CrCl) volunteered to undergo an MR examination that determined renal extraction fraction (EF) with a breathhold inversion recovery echo planar pulse sequence and renal blood flow with a velocity encoded phase imaging sequence. The product of EF and blood flow determines GFR. These values were compared with the 24 h CrCl, estimated GFR by the modification of diet in renal disease (MDRD) regression analysis and the Cockroft-Gault (CG) determination of CrCl. The mean and standard deviation of differences between the MR GFR, MDRD and CG vs the 24 h CrCl were 12.3+/-35.7, -8.9+/-18.5 and 1.2+/-19.6, respectively. The Student t-test showed that none of the mean differences were statistically significant between techniques. This clinical investigation shows that MR can be used for skGFR determination in human subjects with comparable values to those derived from clinically used serum-based GFR estimation techniques.

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Correlation of cine MR velocity measurements in the internal carotid artery with collateral flow in the circle of willis: Preliminary study

Davis

Turski

Gorbatenko

et al. 1993

Magnetic Resonance Imaging

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The velocity-phase relationship intrinsic to phase-contrast magnetic resonance (MR) angiography permits the quantitative and qualitative assessment of blood flow. The ability to measure velocity and vessel cross-sectional area allows noninvasive assessment of volume flow rate (VFR) in the internal carotid artery (ICA). Phase-contrast techniques also demonstrate flow direction. Using two-dimensional cine phase-contrast angiography, the authors evaluated VFR in the ICA and collateral flow about the circle of Willis in 15 patients with ischemic neurologic symptoms. The VFR in each carotid artery was correlated with the degree of stenosis and presence or absence of abnormal circle of Willis collateral flow. There was a correlation between a decrease in VFR and abnormal circle of Willis collateral flow. In addition, a correlation between severe stenosis and a decrease in VFR was found. In patients with ischemic neurologic symptoms without severe stenosis (< 70% diameter stenosis), no decrease in VFR was seen. It is hoped that flow quantification and directional flow imaging with phase-contrast angiography will help further characterize carotid artery occlusive disease by enabling assessment of VFR changes associated with ischemic neurologic symptoms. This study also supports the hypothesis that two mechanisms--hemodynamic and embolic--play a role in ischemic neurologic symptoms.

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Normal Renal Blood Flow Measurement Using Phase-Contrast Cine Magnetic Resonance Imaging

Cited by 41 publications

References 0 publications

Renal artery blood flow: quantification with breath-hold or respiratory triggered phase-contrast MR imaging

Renal artery blood flow: quantification with breath-hold or respiratory triggered phase-contrast MR imaging

MR determination of glomerular filtration rate in subjects with solitary kidneys in comparison to clinical standards of renal function: feasibility and preliminary report

Correlation of cine MR velocity measurements in the internal carotid artery with collateral flow in the circle of willis: Preliminary study

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