Normal Clinical and Biological Parameters of the Common Marmoset (Callithrix jacchus)

Kramer, Robin M; Burns, Monika

doi:10.1016/b978-0-12-811829-0.00006-6

Cited by 10 publications

(12 citation statements)

References 82 publications

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“…Unlike OWMs, the majority of NWMs do not exhibit menses. 41 The reproductive cycles of rhesus macaques and marmosets are closely linked to social structure, frequently resulting in ovarian cycle suppression of subordinate females in group settings. 1,19 The purpose of this study is to provide veterinary pathologists and researchers with an overview of spontaneous urogenital lesions occurring in NHPs during a defined period (30 years) and to compare urogenital lesions occurring in OWMs versus NWMs.…”

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confidence: 99%

Urogenital Lesions in Nonhuman Primates at 2 National Primate Research Centers

et al. 2020

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Given their genetic and anatomic similarities to humans, nonhuman primates (NHPs) may serve as animal models for urogenital diseases of humans. The purpose of this study was to examine the frequency of spontaneous urogenital lesions occurring over a 30-year period at the Yerkes and Southwest National Primate Research Centers and to compare and contrast lesions occurring in Old World versus New World primates. Lesions occurring in the chimpanzee ( Pan troglodytes), baboon ( Papio spp.), rhesus macaque ( Macaca mulatta), cynomolgus macaque ( Macaca fascicularis), pig-tailed macaque ( Macaca nemestrina), sooty mangabey ( Cercocebus atys), common marmoset ( Callithrix jacchus), cotton-top tamarin ( Sanguinus oedipus), and squirrel monkey ( Saimiri sciureus) are discussed. The most common lesions of the kidney were medullary amyloidosis, renal cysts, renal tubular degeneration, glomerulonephritis or glomerulopathy, nephritis, nephrocalcinosis, pyelonephritis, and hydronephrosis. Specific causes of renal tubular disease included pigmentary nephrosis and tubular lipidosis. Renal tumors, including renal adenoma and carcinoma, lymphoma, and nephroblastoma, were infrequent diagnoses in all species. Endometriosis was the most frequently diagnosed lesion of the female genital tract. Of the animals examined in this study, it was most frequent in Old World primates. Leiomyoma was the most common uterine tumor. Granulosa cell tumor was the most frequently observed neoplasm of the ovaries, followed by teratoma. Of animals included in the study, most ovarian tumors occurred in baboons. Neoplasms of the male reproductive tract included interstitial cell tumor, seminoma, penile squamous cell carcinoma, penile papilloma, and histiocytoma. In New World monkeys, renal lesions were reported more frequently than genital lesions.

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confidence: 99%

Urogenital Lesions in Nonhuman Primates at 2 National Primate Research Centers

et al. 2020

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“…Five out of 6 recipients exhibited hypothermia (<36.5°C), 3 were comatose, 2 had low activity, 1 had melena, and 1 was vomiting ( Table 2 ). Blood examinations revealed severe anemia with hematocrit values of 10–22.4%, hypokalemia (<3.5 mEq/l) (3 recipients), hypercreatininemia (>0.4 mg/dl) (2), high blood urea nitrogen (BUN; 25.6 mg/dl) (3), and high alanine aminotransferase (ALT; 14 IU/l) (1) ( Table 2 and Supplementary Table 1 ) [ 1 ]. After transfusions, any hemorrhage was not observed in 5 recipients (R1–4, R6).…”

Section: Resultsmentioning

confidence: 99%

“…The common marmoset (marmoset, Callithrix jacchus ) is a New World primate species frequently used for biomedical research and preclinical studies because it is closely related to humans, small (300–500 g), and reproduces rapidly for a primate [ 1 ]. Recent advances in genetic modification technologies have expanded the species’ research usability as a translational nonhuman primate model [ 2 , 3 , 4 , 5 ].…”

Section: Introductionmentioning

confidence: 99%

Whole blood transfusion in common marmosets: a clinical evaluation

et al. 2022

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In veterinary medicine, blood transfusion is commonly performed on companion animals. The common marmoset is a small nonhuman primate with increasing popularity as an animal model in biomedical research. Because of its small whole blood volume, the marmoset is at high risk of exsanguination, and blood transfusion is required to care for life-threatening bleeding. However, few clinical evaluations exist on transfusions for marmosets. This study performed whole blood transfusion with cross-matching on nine marmosets and surveyed the therapeutic effects. Recipients included clinical cases with persistent bleeding, anemia, and coma, as well as animals subjected to postoperative bleeding prophylaxis. Donors were selected from healthy marmosets, including littermates. Cross-match assay before transfusion were all negative, and recipients showed no visible signs of transfusion-related adverse reactions. Whole blood transfusions caused hemostasis and successful recovery in bleeding marmosets, including long-term improvement of anemia cases. Our results indicated that blood transfusion is effective for marmosets with severe anemia and persistent hemorrhage from both non-experimental and surgical causes. Furthermore, DNA sequencing for blood-group classification revealed that all subject marmosets were type A, suggesting that the risk of blood type mismatch may be low in this species.

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“…DBH is related to the age of the tree [ 31 ], which led the authors to suggest that there is a cycle of use according to the maturity of A. peregrina trees, which can live for 30 years or more [ 32 ]. As wild marmosets live for around 5–7 years [ 33 ], the trees thus exploited remained available for use by several generations of marmosets [ 16 ]. It appears that marmosets are sensitive to the condition of trees, exploiting them in a manner that maintains the availability of food sources.…”

Section: Discussionmentioning

confidence: 99%

Tree Species and Morphology of Holes Caused by Black-Tufted Marmosets to Obtain Exudates: Some Implications for the Exudativory

Lamoglia

Boere

Picoli

et al. 2022

Animals

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Knowledge of the pattern of exploitation of trees can help us understand the relationship between marmosets and plants, especially in declining forests, such as those in the Brazilian Cerrado. Black-tufted marmosets (Callithrix penicillata) regularly exploit exudates by gouging the bark of trees with their specialized teeth. Determining preferred tree species to exploit exudates is important for forest management aimed at maintaining an essential food source for urban marmosets. We characterized the tree species, dendrometry, and the characteristics of the holes made by marmosets to obtain exudates. Based on these data, we proposed a gouging effort index (Chiseling Suitability Index for Marmosets, ChiSI). We identified 16 species belonging to 10 families of trees with gouging marks made by marmosets. Eleven new tree species used by black-tufted marmosets for exudates were identified in urban forests in the Cerrado. Exudate exploration was predominantly of medium intensity, with round holes concentrated in the canopy. The species Tapirira guianensis and Croton urucana were preferred. The ChiSI was characterized by a narrow range for both T. guianensis and C. urucana. Despite the flexibility of obtaining exudates, the black-tufted marmosets concentrate their exploitation to only a few tree species. The T. guianensis and C. urucana tree species should be considered the most important species for management plans and the preservation of black-tufted marmosets that live in urban forests in the Cerrado.

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Normal Clinical and Biological Parameters of the Common Marmoset (Callithrix jacchus)

Cited by 10 publications

References 82 publications

Urogenital Lesions in Nonhuman Primates at 2 National Primate Research Centers

Urogenital Lesions in Nonhuman Primates at 2 National Primate Research Centers

Whole blood transfusion in common marmosets: a clinical evaluation

Tree Species and Morphology of Holes Caused by Black-Tufted Marmosets to Obtain Exudates: Some Implications for the Exudativory

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