Normal breast tissue stiffness measured by a new ultrasound technique: Virtual touch tissue imaging quantification (VTIQ)

Golatta, Michael; Schweitzer-Martin, Mirjam; Harcos, Aba; Schott, Sarah; Junkermann, H.; Rauch, Geraldine; Sohn, Christof; Heil, Joerg

doi:10.1016/j.ejrad.2013.06.029

Cited by 61 publications

(43 citation statements)

References 22 publications

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“…The latest quantitative SWE technique, Virtual Touch tissue imaging quantification (VTIQ) (Siemens Medical Solutions, Mountain View, CA, USA) on ARFI, has the potential to overcome the limitations; thus, it may be more accurate in depicting the actual elasticity of the tissue quantitatively and may be applicable to more patients (Golatta et al 2013;Ianculescu et al 2014;Trottmann et al 2014). With VTIQ, a shear wave quality mode is available and a SWV ROI can be placed in areas with high quality in the nodule, thus avoiding invalid measurements.…”

Section: Discussionmentioning

confidence: 99%

Quantitative Shear Wave Velocity Measurement on Acoustic Radiation Force Impulse Elastography for Differential Diagnosis between Benign and Malignant Thyroid Nodules: A Meta-analysis

Liu

et al. 2015

Ultrasound in Medicine & Biology

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The aim of this study was to evaluate the diagnostic performance of quantitative shear wave velocity (SWV) measurement on acoustic radiation force impulse (ARFI) elastography for differentiation between benign and malignant thyroid nodules using meta-analysis. The databases of PubMed and the Web of Science were searched. Studies published in English on assessment of the sensitivity and specificity of ARFI elastography for the differentiation of thyroid nodules were collected. The quantitative measurement of ARFI elastography was evaluated by SWV (m/s). Meta-Disc Version 1.4 software was used to describe and calculate the sensitivity, specificity, positive likelihood ratio, negative likelihood ratio, diagnostic odds ratio and summary receiver operating characteristic curves. We analyzed a total of 13 studies, which included 1,854 thyroid nodules (including 1,339 benign nodules and 515 malignant nodules) from 1,641 patients. The summary sensitivity and specificity for differential diagnosis between benign and malignant thyroid nodules by SWV were 0.81 (95% confidence interval [CI]: 0.77-0.84) and 0.84 (95% CI: 0.81-0.86), respectively. The pooled positive and negative likelihood ratios were 5.21 (95% CI: 3.56-7.62) and 0.23 (95% CI: 0.17-0.32), respectively. The pooled diagnostic odds ratio was 27.53 (95% CI: 14.58-52.01), and the area under the summary receiver operating characteristic curve was 0.91 (Q* = 0.84). In conclusion, SWV measurement on ARFI elastography has high sensitivity and specificity for differential diagnosis between benign and malignant thyroid nodules and can be used in combination with conventional ultrasound.

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Section: Discussionmentioning

confidence: 99%

Quantitative Shear Wave Velocity Measurement on Acoustic Radiation Force Impulse Elastography for Differential Diagnosis between Benign and Malignant Thyroid Nodules: A Meta-analysis

Liu

et al. 2015

Ultrasound in Medicine & Biology

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“…Various studies have showed that conventional US may be helpful for predicting axillary LNM by evaluating the suspicious US features such as intralesional calcification, internal flow, and nodal size 8, 9 . On the other hand, many studies have showed that breast cancers are stiffer than normal and benign tissues 10–12 , which can be evaluated by US elastography. As new US-based elastography techniques, acoustic radiation force impulse (ARFI) imaging of virtual touch tissue imaging (VTI; Siemens Medical Solutions, Mountain View, CA, USA) and shear wave imaging of virtual touch tissue imaging & quantification (VTIQ; Siemens Medical Solutions, Mountain View, CA, USA) have recently been used to diagnose breast cancers by measurement of the tissue stiffness 10, 11 .…”

Section: Introductionmentioning

confidence: 99%

A Risk Model based on Ultrasound, Ultrasound Elastography, and Histologic Parameters for Predicting Axillary Lymph Node Metastasis in Breast Invasive Ductal Carcinoma

et al. 2017

Sci Rep

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To develop a risk model for predicting axillary lymph node metastasis (LNM) in patients with breast invasive ductal carcinoma (IDCs) using ultrasound (US), US elastography of virtual touch tissue imaging (VTI) and virtual touch tissue imaging & quantification (VTIQ), and histologic parameters. This study included 162 breast IDCs in 162 patients. Univariate and multivariate analyses were used to identify the risk factors and a risk model was created. The results found that 64 (39.5%) of 162 patients had axillary LNMs. The risk score (RS) for axillary LNM was defined as following: RS = 1.3 × (if lesion size ≥20 mm) + 2.6 × (if taller than wide shape) + 2.2 × (if VTI score ≥5) + 3.9 × (if histological grade III) + 1.9 × (if positive C-erbB-2). The rating system was divided into 6 stages (i.e. Stage I, Stage II, Stage III, Stage IV, Stage V, and Stage VI) and the associated risk rates in terms of axillary LNM were 0% (0/19), 6.1% (2/33), 7.7% (3/39), 65.5% (19/29), 92.3% (24/26), and 100% (16/16), respectively. The risk model for axillary LNM established in the study may facilitate subsequent treatment planning and management in patients with breast IDCs.

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“…So far, VTQ values, namely, shear wave velocities, have been reported for lesions in such organs as the breast (Saleem 2009), liver (Shuang et al 2011), kidney (Clevert et al 2009) and thyroid (Gu et al 2012). In addition, VTQ has also been used to determine normal stiffness of tissues in various organs (Goertz et al 2011;Golatta et al 2013;Sporea et al 2011).…”

Section: Introductionmentioning

confidence: 99%

Diagnosis of Thyroid Nodules Using Virtual Touch Tissue Quantification Value and Anteroposterior/Transverse Diameter Ratio

Zhou

Zhang

et al. 2015

Ultrasound in Medicine & Biology

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Normal breast tissue stiffness measured by a new ultrasound technique: Virtual touch tissue imaging quantification (VTIQ)

Cited by 61 publications

References 22 publications

Quantitative Shear Wave Velocity Measurement on Acoustic Radiation Force Impulse Elastography for Differential Diagnosis between Benign and Malignant Thyroid Nodules: A Meta-analysis

Quantitative Shear Wave Velocity Measurement on Acoustic Radiation Force Impulse Elastography for Differential Diagnosis between Benign and Malignant Thyroid Nodules: A Meta-analysis

A Risk Model based on Ultrasound, Ultrasound Elastography, and Histologic Parameters for Predicting Axillary Lymph Node Metastasis in Breast Invasive Ductal Carcinoma

Diagnosis of Thyroid Nodules Using Virtual Touch Tissue Quantification Value and Anteroposterior/Transverse Diameter Ratio

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