Nonthermal Ultrasound and Exercise in Skeletal Muscle Regeneration

Markert, Chad D.; Merrick, Mark A.; Kirby, Timothy E.; Devor, Steven T.

doi:10.1016/j.apmr.2004.12.037

Cited by 74 publications

(45 citation statements)

References 41 publications

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“…Upon continuous ultrasound (frequency, 1 MHz; intensity, 1.5 W/cm 2 ) application at the medial gastrocnemius muscle for 10 min in humans, the mean temperature reached 40.3 °C, which was an increase of 4.9 °C (Draper et al, 1993a). Therapeutic ultrasound focuses primarily on the alteration of extensibility of collagenous tissues in order to improve ROM (Markert et al, 2005); therefore, this treatment is widely utilized to treat joint contracture in a rehabilitative setting. Little is known, however, regarding the effects of therapeutic ultrasound on collagen fibril arrangement in the 7 endomysium of immobilized muscle.…”

Section: Introductionmentioning

confidence: 99%

Effects of Therapeutic Ultrasound on Joint Mobility and Collagen Fibril Arrangement in the Endomysium of Immobilized Rat Soleus Muscle

Okita

Nakano

Kataoka³

et al. 2009

Ultrasound in Medicine & Biology

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This study examined effects of therapeutic ultrasound on joint mobility and collagen fibril arrangement in the endomysium of immobilized rat soleus muscle.Twenty-two male Wistar rats were divided randomly into control (n=5) and experimental groups (n=17).In the experimental group, bilateral ankle joints of each rat were fixed in full plantar flexion with a plaster cast over a 4-wk period.Five animals in the experimental group were immobilized throughout the 4-wk (immobilization group) period, whereas the remaining rats in the experimental group were randomly divided into the ultrasound (US, n=6) and sham (n=6) treatment groups.Under anesthesia, continuous ultrasonic energy (frequency, 1 MHz; intensity, 1.0 W/cm 2 ) was delivered to the triceps surae muscle of the US group for 15 min per d, 6 d per wk over the 4-wk immobilization period. Ultrasonic energy was not delivered to the triceps surae muscle in sham animals; only the transducer head was moved.Ankle joint mobility on dorsiflexion in the immobilization, sham and US groups was significantly smaller than that of the control group, whereas in the US group, this parameter was significantly greater than in the immobilization and sham groups.Collagen fibril arrangement in the endomysium of the control and US groups was longitudinal to the axis of the muscle fibers; in contrast, it was circumferential in the immobilization and sham groups. Our findings revealed that joint immobilization induces decreased joint mobility and collagen fibril movement in the endomysium; 3 furthermore, ultrasound treatment can prevent these changes. We hypothesized that therapeutic ultrasound during the immobilization process may inhibit deterioration of muscle contracture.

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Section: Introductionmentioning

confidence: 99%

Effects of Therapeutic Ultrasound on Joint Mobility and Collagen Fibril Arrangement in the Endomysium of Immobilized Rat Soleus Muscle

Okita

Nakano

Kataoka³

et al. 2009

Ultrasound in Medicine & Biology

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“…Despite the excellent capacity of muscle tissue to regenerate after injury, in critical situations such as extensive myofibrilar degeneration or poorly vascularized injuries, the process of muscle healing can be delayed [8][9]. In this context, there is a need to develop treatments able to accelerate muscle cell proliferation and prevent fibrosis during the healing process, which would decrease the rehabilitation time and regenerative processes, producing a return to the previous level of function as quickly and thoroughly as possible [9][10].…”

Section: Introductionmentioning

confidence: 99%

Effects of 660 nm low-level laser therapy on muscle healing process after cryolesion

Rodrigues

Assis²,

Fernandes³

et al. 2013

J Rehabil Res Dev

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Abstract-The aim of this study was to evaluate the effects of 660 nm low-level laser therapy (LLLT) on muscle regeneration after cryolesion in rat tibialis anterior muscle. Sixty-three Wistar rats were divided into a control group, 10 J/cm 2 lasertreated group, and 50 J/cm 2 laser-treated group. Each group formed three subgroups (n = 7 per group), and the animals were sacrificed 7, 14, or 21 d after lesion. Histopathological findings revealed a lower inflammatory process in the lasertreated groups after 7 d. After 14 d, irradiated animals at both fluences showed higher granulation tissue, new muscle fibers, and organized muscle structure. After 21 d, full tissue repair was observed in all groups. Moreover, irradiated animals at both fluences showed smaller necrosis area in the first experimental period evaluated. MyoD immunoexpression was observed in both treated groups 7 d postinjury. Myogenin immunoexpression was detected after 7 and 14 d. The higher fluence increased the number of blood vessels after 14 and 21 d. These results suggest that LLLT, at both fluences, positively affects injured skeletal muscle in rats, accelerating the muscle-regeneration process.

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“…El ultrasonido terapéutico (US) se recomienda y usa frecuentemente en el tratamiento de lesiones musculares en numerosas guías clínicas, aunque los datos científicos obtenidos a partir de estudios en animales no muestran eficacia sustancial científicamente soportada ni evidencia clínica para la recomendación directa de este perfil clínico, si bien es cierto que los estudios no poseen calidad metodológica suficiente , sobre modo de aplicación, dosificación y patrones de desarrollo 24,25,26 Sin embargo, a pesar de la aparente promoción de la regeneración de tejido basado en los efectos mecánicos y térmicos del US, durante la fase de proliferación de la mi regeneración 24 , el US terapéutico no parece tener efecto positivo en el resultado final de la curación muscular 24,25,26 por lo que se precisan de estudios solidos que aporten un mayor conocimiento del mismo.…”

Section: Electroterapia Terapéutica Corrientes Antialgicas Y Ultrasounclassified

Lesión muscular en podología. Actualización en patofisiología y terapéutica

Sanz

López‐López

Palomo‐López

et al. 2015

Rev. Int. Cienc. Podol.

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Nonthermal Ultrasound and Exercise in Skeletal Muscle Regeneration

Cited by 74 publications

References 41 publications

Effects of Therapeutic Ultrasound on Joint Mobility and Collagen Fibril Arrangement in the Endomysium of Immobilized Rat Soleus Muscle

Effects of Therapeutic Ultrasound on Joint Mobility and Collagen Fibril Arrangement in the Endomysium of Immobilized Rat Soleus Muscle

Effects of 660 nm low-level laser therapy on muscle healing process after cryolesion

Lesión muscular en podología. Actualización en patofisiología y terapéutica

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