Nonsurgical Transurethral Radiofrequency Collagen Denaturation: Results at Three Years after Treatment

Abstract

Objective. To assess treatment efficacy and quality of life in women with stress urinary incontinence 3 years after treatment with nonsurgical transurethral radiofrequency collagen denaturation. Methods. This prospective study included 139 women with stress urinary incontinence due to bladder outlet hypermobility. Radiofrequency collagen denaturation was performed using local anesthesia in an office setting. Assessments included incontinence quality of life (I-QOL) and urogenital distress inventory (UDI-6) instruments. Results. In total, 139 women were enrolled and 136 women were treated (mean age, 47 years). At 36 months, intent-to-treat analysis (n = 139) revealed significant improvements in quality of life. Mean I-QOL score improved 17 points from baseline (P = .0004), while mean UDI-6 score improved (decreased) 19 points (P = .0005). Conclusions. Transurethral collagen denaturation is a low-risk, office-based procedure that results in durable quality-of-life improvements in a significant proportion of women for as long as 3 years.

Cost effectiveness of radiofrequency microremodeling for stress urinary incontinence

“…Efficacy measured by pad test ranged from 35 % over a 36-month period [4] to 92 % over a 12-month period [12]. Four studies used a 1-h pad test and defined dry as <1 or <2 g, one used a 20-min pad test, and two used a 24-h pad test.…”

Radiofrequência Não Ablativa No Tratamento Da Incontinência Urinária De Esforço

“…(33) A radiofrequência é uma técnica preconizada no tratamento para produção de colágeno cutâneo e intra-uretral, não apresentando rotineiramente reações adversas importantes, além de vermelhidão local ou leve edema, foram relatadas algumas complicações transitórias como disúria, infecção urinária, hematúria e disúria. (30,32,33)…”

“…Após a conclusão do último ciclo, o balão é desinsuflado e a agulha era retirada. (30) Todo o tratamento incluído o posicionamento da paciente e aplicação da radiofrequência durou aproximadamente 20 minutos. Foram tratadas um total de 110 pacientes, 63 pacientes passaram pelo mesmo procedimento sem no entanto ocorrer a emissão da radiofrequência (grupo controle), a média de idade das pacientes foi de 50 anos.…”

Stress Urinary Incontinence and Overactive Bladder Syndrome: Current Options and New Targets for Management

“…Three-year durability results of a multicenter trial were recently published. 13 In the trial, 136 women (mean age, 47 years) with a clinical diagnosis of SUI underwent treatment. The subjects had failed prior conservative therapy and had not undergone prior surgical treatment.…”