Nonsurgical Transurethral Collagen Denaturation for Stress Urinary Incontinence in Women: 12-Month Results from a Prospective Long-term Study

Elser, Denise M.; Mitchell, G.K.; Miklos, John R.; Nickell, Kevin G.; Cline, Kevin; Winkler, Harvey A.; Wells, W. Glen

doi:10.1016/j.jmig.2008.09.621

Cited by 17 publications

(21 citation statements)

References 27 publications

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“…This interim analysis supports previously reported studies 4,6,7,14 demonstrating the efficacy and safety of transurethral collagen denaturation as a nonsurgical treatment option for women with SUI. This minimally invasive procedure can be performed under local anesthesia in a physician's office and requires negligible recovery time, making it an attractive treatment option.…”

Section: Discussionsupporting

confidence: 88%

“…These results confirm earlier 12-month findings from this study. 4 Results at 18 months reveal consistent, significant improvement in urinary continence. Approximately half of the patients reported that the frequency of SUI episodes decreased by at least 50% versus baseline following treatment.…”

Section: Discussionmentioning

confidence: 83%

“…Between previously published results at 12 months 4 and current evaluations at 18 months, 12 patients withdrew from the study. Subsequently, 63 patients completed the 18-month follow-up visit, with data available for 60 patients.…”

Section: Patientsmentioning

confidence: 99%

“…Subsequently, 63 patients completed the 18-month follow-up visit, with data available for 60 patients. The ITT analysis identified no Reprinted from Elser et al, 4 with permission from Elsevier.…”

Section: Patientsmentioning

confidence: 99%

“…This procedure, approved by the FDA in 2005, can be performed in about 30 min (total visit time approximately 1 hr) in an office setting or ambulatory surgical center using local anesthesia without incisions or the assistance of any visualization or imaging technique. 4,5 The procedure reduces regional dynamic tissue compliance without creating strictures or reducing luminal caliber, leading to a functional This report describes 18-month results from an ongoing 3-year study designed to prospectively assess the efficacy and safety of transurethral collagen denaturation and the durability of these results.…”

Section: Introductionmentioning

confidence: 99%

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Nonsurgical transurethral collagen denaturation for stress urinary incontinence in women: 18‐month results from a prospective long‐term study

Elser

Mitchell

Miklos

et al. 2010

Neurourology and Urodynamics

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Section: Discussionsupporting

confidence: 88%

Section: Discussionmentioning

confidence: 83%

Section: Patientsmentioning

confidence: 99%

Section: Patientsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Nonsurgical transurethral collagen denaturation for stress urinary incontinence in women: 18‐month results from a prospective long‐term study

Elser

Mitchell

Miklos

et al. 2010

Neurourology and Urodynamics

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Transurethral radiofrequency collagen denaturation for the treatment of women with urinary incontinence

Kang

Han

Neuberger

et al. 2015

Cochrane Database of Systematic Reviews

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⊕⊕ Low a,d *The basis for the assumed risk (e.g. median control group risk across studies) is provided in footnotes. The corresponding risk (and its 95% CI) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI). CI: Confidence interval; MD: Mean difference; I-QOL: Incontinence Quality of Life; RCT: Randomised controlled trial; RR: Risk ratio; UI: Urinary incontinence. GRADE Working Group grades of evidence. High quality: Further research is very unlikely to change our confidence in the estimate of effect. Moderate quality: Further research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate. Low quality: Further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate. Very low quality: We are very uncertain about the estimate. a Downgraded for study limitations (-1): high risk of bias. b Downgraded for imprecision (-1): no events in small study. c Downgraded for imprecision (-1): confidence interval includes both no effect and appreciable benefit; low numbers of events. d Downgraded for imprecision (-1): confidence interval includes no effect and both appreciable benefit and appreciable harm; low numbers of events. 5 Transurethral radiofrequency collagen denaturation for the treatment of women with urinary incontinence (Review)

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Belastungsinkontinenz der Frau im Alter

Loertzer¹,

Schneider²

2013

Urologe

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Stress incontinence is one of the major challenges in geriatric medicine. This is becoming more apparent in routine urology practice with the demographic changes in the population. A thorough diagnosis for a correct treatment of stress incontinence is as important in elderly women as it is in younger patients. This includes assessing the risk factors of incontinence and obesity, parturition, pelvic surgery and changes in hormone levels are risk factors usually found in elderly women. These are the main reasons why this patient group is most frequently affected. Treatment options do not differ significantly from these of younger women. Lifestyle modification, weight loss and supervised pelvic floor training are the mainstays of conservative therapy and surgical treatment should only be considered after these options have been exhausted. In these cases minimally invasive surgical techniques offer clear advantages especially for elderly often multimorbid women.

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Nonsurgical Transurethral Collagen Denaturation for Stress Urinary Incontinence in Women: 12-Month Results from a Prospective Long-term Study

Cited by 17 publications

References 27 publications

Nonsurgical transurethral collagen denaturation for stress urinary incontinence in women: 18‐month results from a prospective long‐term study

Nonsurgical transurethral collagen denaturation for stress urinary incontinence in women: 18‐month results from a prospective long‐term study

Transurethral radiofrequency collagen denaturation for the treatment of women with urinary incontinence

Belastungsinkontinenz der Frau im Alter

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