Nonsuppurative Nodular Panniculitis of the Breast

Rotaru, Natalia; Punga, Janna; Codreanu, Ion; Gavrilasenco, I.; Diana, Manea; Cujba, Natalia

doi:10.1016/j.clbc.2015.02.004

Cited by 3 publications

(4 citation statements)

References 20 publications

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“…Rotaru et al reported a case of non-suppurative nodular breast panniculitis with systemic symptoms. After treated with systemic corticosteroids, the condition improved (15). Yuan reported a case of isolated breast panniculitis without evidence of systemic inflammation, who underwent resection without systemic corticosteroid or immunosuppressive therapy (16).…”

Section: Discussionmentioning

confidence: 99%

Breast panniculitis with liquefactive fat necrosis: A case report

Zhang

Shi

2018

Exp Ther Med

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Panniculitis is a group of heterogeneous disorders characterized by inflammation of the subcutaneous adipose tissue. Panniculitis of breast tissue as the initial manifestation has rarely been reported and is often misdiagnosed. Breast panniculitis may cause substantial morbidity and early diagnosis and treatment are important for the prognosis of the disease. The present study has reported a case of panniculitis with inflammation of the mammary glands as the initial presentation and provided a detailed description of ultrasonography, X-ray, computed tomography, magnetic resonance imaging and other imaging features of breast panniculitis. The treatment and follow-up were also described. Following treatment with systemic corticosteroids combined with methotrexate and thalidomide for 2 months, the breast appeared to be normal without scar formation. The present case report provides a good reference for the future diagnosis and treatment of breast panniculitis.

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Section: Discussionmentioning

confidence: 99%

Breast panniculitis with liquefactive fat necrosis: A case report

Zhang

Shi

2018

Exp Ther Med

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“…It is difficult to diagnose, both clinically and histologically [ 1 ]. Secondary panniculitis can affect people of all ages and is more prevalent in females [ 2 ]. Clinically, it presents tender, raised, red-colored, warm nodules, frequently localized in the lower extremities and trunk.…”

Section: Discussionmentioning

confidence: 99%

“…Histologically, the lesion has an inflammatory infiltrate, blood vessels, and fibrous septa. Panniculits could be lobar or septal with or without vascular involvement, and is classified as septal panniculitis and mixed lobar panniculitis with or without vasculitis [ 2 , 3 ]. It is considered to be a non-neoplastic, benign process.…”

Section: Discussionmentioning

confidence: 99%

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A solitary presentation of panniculitis in a patient with a history of breast cancer

Garcia-Hernandez

López‐García

Huerta

et al. 2018

Annals of Medicine and Surgery

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IntroductionPanniculits presents as an inflammation of the subcutaneous adipose tissue of the skin. In breast, panniculitis is very rare and is usually a manifestation of underlying inflammatory conditions. The typical presentation is palpable tender nodules, which in cases of breast panniculitis, triggers an extensive work up to exclude a malignancy. Herein we present a case of septal and lobar panniculitis in a female with clinical history of invasive ductal carcinoma.Presentation of the caseA 52-year old female with past medical history of invasive breast carcinoma 5 years prior to the presentation. The patient's chief complaint was a 1-year history of a subcutaneous nodular lesion on her left breast. A core biopsy of the firm nodule showed marked inflammation of the breast. A second skin biopsy showed an abundant chronic inflammatory infiltrate, with lymphocytic vasculitis and neuritis, suggestive of an underlying autoimmune process.DiscussionSubcutaneous panniculitis with or without vasculitis is a rare condition when presenting in the breast. Panniculitis can mimic malignancy and thus, it is important to differentially diagnose it from breast carcinoma. Histologically, it is classified in lobular and septal lymphocytic panniculitis depending on specific diagnostic characteristics.ConclusionPanniculitis of the breast is a rare condition that needs to be included in the differential diagnosis of subcutaneous breast masses. In all cases, but specifically in females with history of breast cancer, panniculitis still should be thought of as a possibility, and imaging as well as other diagnostic techniques can aid in making the correct diagnosis.

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