Breast panniculitis with liquefactive fat necrosis: A case report

Abstract

Panniculitis is a group of heterogeneous disorders characterized by inflammation of the subcutaneous adipose tissue. Panniculitis of breast tissue as the initial manifestation has rarely been reported and is often misdiagnosed. Breast panniculitis may cause substantial morbidity and early diagnosis and treatment are important for the prognosis of the disease. The present study has reported a case of panniculitis with inflammation of the mammary glands as the initial presentation and provided a detailed description of ultrasonography, X-ray, computed tomography, magnetic resonance imaging and other imaging features of breast panniculitis. The treatment and follow-up were also described. Following treatment with systemic corticosteroids combined with methotrexate and thalidomide for 2 months, the breast appeared to be normal without scar formation. The present case report provides a good reference for the future diagnosis and treatment of breast panniculitis.

Inter‐ and Intra‐rater Agreement of Dermatologic Ultrasound for the Diagnosis of Lobular and Septal Panniculitis

“…This is the reason why implementation of noninvasive techniques such as dermatologic US examinations is desirable. Dermatologic US can provide information about the predominantly septal or lobular nature of the panniculitis and additionally about the presence of additional signs such as fat necrosis, calcium deposition, and venous dilalation . It is a noninvasive test that can even be repeated during the clinical course of the lesions, adding dynamic information about their evolution.…”

“…Dermatologic US can provide information about the predominantly septal or lobular nature of the panniculitis and additionally about the presence of additional signs such as fat necrosis, calcium deposition, and venous dilalation. [4][5][6] It is a noninvasive test that can even be repeated during the clinical course of the lesions, adding dynamic information about their evolution. In our setting, the most frequently diagnosed form of panniculitis is erythema nodosum, followed by sclerosing panniculitis and nodular vasculitis/ erythema induratum of Bazin.…”

Pannikulitis der Mamma – eine seltene Differenzialdiagnose der Mamma

“…Therapeutisch sind bis dato noch keine etablierten Therapieregime für die Pannikulitis der Mamma beschrieben worden. In vielen Fällen scheint aufgrund des Verdachts eines Malignoms ein chirurgisches Verfahren zur histologischen Sicherung und Resektion gewählt worden zu sein [5]. Prinzipiell wird nach der histopathologischen Sicherung eine Immunsuppression durchgeführt, um die primär als autoimmun verursachte Entzündungsreaktion zu hemmen.…”