Case PresentationThe electrocardiogram (ECG) presented in Figure 1 was obtained from a 62-year-old woman, with a 10-year history of heart palpitations and several syncopal and presyncopal episodes in the last few months, who was referred for electrophysiological study and pacemaker implantation. The echocardiogram was unremarkable apart from moderate tricuspid regurgitation. A nonarrhythmia ECG was also normal with a PR interval of 160 milliseconds. She presented with almost permanent irregular supraventricular tachyarrhythmia at 120-170 bpm, interspersed with frequent supraventricular ectopy (several thousand per 24 hour) and periods of pronounced paroxysmal first degree atrioventricular (AV) block with a PR of approximately 600 milliseconds (Fig. 1). Is it possible that a single mechanism underlies all of the observed ECG phenomena? Figure 1. A resting electrocardiogram typical for the current patient demonstrating supraventricular arrhythmia and an episode of pronounced first-degree AV block.