Nonneoplastic lesions of the ovary in Fischer 344 rats and B6C3F1 mice.

Montgomery, Charles A.; Alison, Roger H.

doi:10.1289/ehp.877353

Cited by 14 publications

(5 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…31 Davis et al (1999), 66 Greaves (2012), 69 Greaves et al (1992), 114 Long (2002), 133 Montgomery and Alison (1987), 55 Genadry et al (1977), 108 Lee et al (2011), 24 Clow et al (2002), 207 Wenzel and Odend’hal (1985)…”

Section: Morphologymentioning

confidence: 99%

“… 32 Davis et al (2001), 39 Dixon et al (1999), 133 Montgomery and Alison (1987), 155 Peluso and Gordon (1992), 114 Long (2002)…”

Section: Morphologymentioning

confidence: 99%

“…5 Alison et al (1990), 31 Davis et al (1999), 32 Davis et al. (2001), 39 Dixon et al (1999), 112 Lewis (1987), 115 Long et al (2001), 133 Montgomery and Alison (1987)…”

Section: Morphologymentioning

confidence: 99%

See 2 more Smart Citations

Nonproliferative and Proliferative Lesions of the Rat and Mouse Female Reproductive System

Alison²,

et al. 2014

View full text Add to dashboard Cite

The INHAND (International Harmonization of Nomenclature and Diagnostic Criteria for Lesions in Rats and Mice) Project (www.toxpath.org/inhand.asp) is a joint initiative of the Societies of Toxicological Pathology from Europe (ESTP), Great Britain (BSTP), Japan (JSTP) and North America (STP) to develop an internationally accepted nomenclature for proliferative and nonproliferative lesions in laboratory animals. The purpose of this publication is to provide a standardized nomenclature for classifying microscopic lesions observed in the female reproductive tract of laboratory rats and mice, with color photomicrographs illustrating examples of some lesions. The standardized nomenclature presented in this document is also available electronically on the internet (http://www.goreni.org/). Sources of material included histopathology databases from government, academia, and industrial laboratories throughout the world. Content includes spontaneous and aging lesions as well as lesions induced by exposure to test materials. There is also a section on normal cyclical changes observed in the ovary, uterus, cervix and vagina to compare normal physiological changes with pathological lesions. A widely accepted and utilized international harmonization of nomenclature for female reproductive tract lesions in laboratory animals will decrease confusion among regulatory and scientific research organizations in different countries and provide a common language to increase and enrich international exchanges of information among toxicologists and pathologists.

show abstract

Section: Morphologymentioning

confidence: 99%

“… 32 Davis et al (2001), 39 Dixon et al (1999), 133 Montgomery and Alison (1987), 155 Peluso and Gordon (1992), 114 Long (2002)…”

Section: Morphologymentioning

confidence: 99%

See 1 more Smart Citation

Nonproliferative and Proliferative Lesions of the Rat and Mouse Female Reproductive System

Alison²,

et al. 2014

View full text Add to dashboard Cite

show abstract

“…Hyperplasia in the epithelial tubules and cords in the thymus, which is stimulated by estrogens 35 , occurred more often in the HAA rats than in the LAA rats. Hyperplasia of the sex cord-stromal or Sertoli cells in the ovary, which is thought to be associated with a deficiency in gonadotropins 36 , was also observed in the HAA rats. Moreover, uterine polyps occurred more often in the HAA rats than in the LAA rats.…”

Section: Discussionmentioning

confidence: 81%

Stress-reactive rats (high-avoidance female rats) have a shorter lifespan than stress-nonreactive rats (low-avoidance female rats)

et al. 2016

View full text Add to dashboard Cite

Although Hatano high-avoidance and low-avoidance rats (HAA and LAA, respectively) have been selectively bred for good versus poor avoidance learning, HAA rats are known to be more reactive to stress than LAA rats. In this study, HAA and LAA female rats were compared during reproductive aging by observing estrous cycles from 8 to 11 months of age. Furthermore, these rats were allowed to live out their natural lifespans, that is, until 24 months of age, in order to compare their survival and to clarify the relationship between reproductive aging and tumor development. At eight months of age, 2 of 35 HAA rats and 20 of 35 LAA rats had abnormal estrous cycles. The median lifespan of the HAA rats (673 days) was shorter than that of the LAA rats (733 days). The incidence of pituitary neoplasia was higher in the HAA rats than in the LAA rats. These results suggest that HAA female rats (i.e., stress-reactive rats) have a shorter lifespan than LAA female rats (i.e., stress-nonreactive rats) and develop pituitary neoplasia, which was one of the causal factors in their accelerated mortality. However, the onset of an age-matched abnormal cycle did not correspond with their lifespan.

show abstract

“…This lesion has been identified in humans (Idress et al . ), rodents (Montgomery & Alison ) and cattle (Edwards ; Santos et al . ).…”

mentioning

confidence: 99%

First report of ovarian epidermoid cyst in a teleost

Silveira

Viott

Santos

et al. 2015

Journal of Fish Diseases

View full text Add to dashboard Cite

Nonneoplastic lesions of the ovary in Fischer 344 rats and B6C3F1 mice.

Cited by 14 publications

References 25 publications

Nonproliferative and Proliferative Lesions of the Rat and Mouse Female Reproductive System

Nonproliferative and Proliferative Lesions of the Rat and Mouse Female Reproductive System

Stress-reactive rats (high-avoidance female rats) have a shorter lifespan than stress-nonreactive rats (low-avoidance female rats)

First report of ovarian epidermoid cyst in a teleost

Contact Info

Product

Resources

About