Nonlinear chromatography Recent theoretical and experimental results

Guiochon, Georges; Ghodbane, Samir; Golshan-Shirazi, Sadroddin; Huang, Jiangen; Katti, Anita M.; Lin, Bingcheng; Ma, Zaitian

doi:10.1016/0039-9140(89)80079-7

Cited by 40 publications

(20 citation statements)

References 16 publications

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“…1) is known to be a convex isotherm such as a Langmuir isotherm and the concave peak shape with tailing in Figure 2 is explained due to the decreasing influence of the column efficiency with an increasing of the loading factor at a low concentration of the eluent. [7][8][9] In these eluent conditions, column capacities were measured from the loading factors using equations (1) and (2). 7,8 Where, L f is the loading factor, t f is the retention time of the peak, t p is the injection time of the sample solution, t r,o and t o are the retention times of the analytical sample size and at a solvent peak, respectively, C mo is the concentration of the sample injected, and V is the volume of the sample injected.…”

Section: Resultsmentioning

confidence: 99%

Separation of Burnup Monitors in Spent Nuclear Fuel Samples by Liquid Chromatography

Joe

Jeon²,

Kim³

et al. 2005

Bulletin of the Korean Chemical Society

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A coupled column liquid chromatography system was applied for the separation of the burnup monitors in spent nuclear fuel sample solutions. A reversed phase column was studied for the adsorption behavior of uranyl ions using alpha-hydroxyisobutyric acid as an eluent and used for the separation of plutonium and uranium. A cation exchange column prepared by coating 1-eicosylsulfate onto the reversed phase column was used for the separation of the lanthanides. In addition, retention of Np was checked with the reversed phase column and cation exchange column, respectively, according to the oxidation states to observe the interference effect for the separation of burnup monitors. This chromatography system showed a great reduction in separation time compared to a conventional anion exchange method. A good agreement from the burnup data was obtained between for this method and a conventional anion exchange method to within 1% of a difference for the spent nuclear fuel samples of about 40 GWD/MTU.

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Section: Resultsmentioning

confidence: 99%

Separation of Burnup Monitors in Spent Nuclear Fuel Samples by Liquid Chromatography

Joe

Jeon²,

Kim³

et al. 2005

Bulletin of the Korean Chemical Society

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“…Firstly, initial state of chromatography column in the δ-pulse method, which injection function was a kind of δ-function, was typically empty. So in the case of δ-Pulse, 1 c satisfied the following initial-boundary problem.…”

Section: δ-Pulse Injectionmentioning

confidence: 97%

“…The relationships among the chromatographic input-output and the system conditions play the very important role in chromatography model [1]- [6].…”

Section: Introductionmentioning

confidence: 99%

Concentration Wave for a Class of Reaction Chromatography System with Pulse Injections

Zhang¹,

Shao²,

Pan³

2016

AJCM

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By using fluid dynamics theory with the effects of adsorption and reaction, the chromatography model with a reaction A → B was established as a system of two hyperbolic partial differential equations (PDE's). In some practical situations, the reaction chromatography model was simplified a semi-coupled system of two linear hyperbolic PDE's. In which, the reactant concentration wave model was the initial-boundary value problem of a self-closed hyperbolic PDE, while the resultant concentration wave model was the initial-boundary value problem of hyperbolic PDE coupling reactant concentration. The general explicit expressions for the concentration wave of the reactants and resultants were derived by Laplace transform. The δ-pulse and wide pulse injections were taken as the examples to discuss detailedly, and then the stability analysis between the resultant solutions of the two modes of pulse injection was further discussed. It was significant for further analysis of chromatography, optimizing chromatographic separation, determining the physical and chemical characters.

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“…Dieses Model1 wurde in den letzten Jahren erfolgreich zur Beschreibung der Trennung einer ganzen Reihe unterschiedlicher Stoffgemische eingesetzt [9, 21. Fur die Berechnung chromatographischer Trennungen stellt die Kenntnis der das Verteilungsgleichgewicht beschreibenden Adsorptionsisothermen q(4 eine wesentliche Voraussetzung dar. Zur Quantifizierung der Gleichgewichtsbeladung einer Komponente i hat sich fur energetisch heterogene Oberflachen folgende, auf der Langmuir-Gleichung aufbauende, jedoch zwei Arten unterschiedlicher Adsorptionszentren bilanzierende Gleichung bewahrt [9] : Diese Gleichung enthalt fur jede Komponente vier freie Parameter. Es handelt sich um die Sattigungsbeladungen der beiden Zentren q: und q: sowie um die Konstanten b' und b2.…”

Section: Modellierung Der Praparativen Chromatographieunclassified

“…Seit denklassischenArbeitenvonVAN DEEMTERet al [lo] ist gut bekannt, da13 die Trennstufenzahl N eine Funktion der Geschwindigkeit u in der Saule ist. Eine grobe Abschatzung des Zusammenhanges N ( u ) ist mit der dimensionslosen Knox-Gleichung [9] moglich: 2 v v 10…”

Section: Modellierung Der Praparativen Chromatographieunclassified

Vergleich verschiedener verfahrenstechnischer Konzepte der präparativen Flüssigchromatographie

Heuer

Kniep

Falk

et al. 1997

Chemie Ingenieur Technik

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Liquid chromatography utilising porous solid phases (adsorption chromatography) is one of the most powerful and versatile methods of modern analytical chemistry. Its widespread application is due in part to the development of a broad range of combinations of solid stationary and liquid mobile phase. Normal phase and reverse phase chromatography with pure and chemically modified silica gel, respectively, affinity chromatography, and ion chromatography can be cited as examples [1]. In addition to its use as an analytical method, chromatography is becoming increasingly important in the preparative‐scale isolation of pure substances in the pharmaceutical industry, in biotechnology, and in the production of fine chemicals. In many cases, the required purity criteria can only be met with chromatographic techniques, as in the resolution of racemates. From a process engineering viewpoint, a better understanding of concentration profile deformations caused by intended overloading of separation columns has recently been acquired [2]. In particular, this cncerns the description of displacement and entrainment effects associated with the competing adsorption. A series of alternative operating modes has been developed and used [3] for enhancing yields and productivities. In spite of a number of attempted comparative studies [4] there is a lack of quantitative information about optimized process. This article aims to compare four different process engineering concepts of preparative chromatography on the basis of a uniform theoretical model.

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Nonlinear chromatography Recent theoretical and experimental results

Cited by 40 publications

References 16 publications

Separation of Burnup Monitors in Spent Nuclear Fuel Samples by Liquid Chromatography

Separation of Burnup Monitors in Spent Nuclear Fuel Samples by Liquid Chromatography

Concentration Wave for a Class of Reaction Chromatography System with Pulse Injections

Vergleich verschiedener verfahrenstechnischer Konzepte der präparativen Flüssigchromatographie

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