Noninvasive evaluation of global and regional left ventricular function using computed tomography and magnetic resonance imaging: a meta-analysis

Kaniewska, Malwina; Schuetz, Georg M.; Willun, Steffen; Dewey, Marc

doi:10.1007/s00330-016-4513-1

Cited by 18 publications

(20 citation statements)

References 86 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Overall, the values of the LV functional indicators were within the reference ranges provided by the analysis software, indicating that the values of these indicators were similar to human levels. These results further support that clinically, the third-generation DSCT, or multidetector computed tomography (MDCT) method, offers good agreement with MRI in assessing LV function [14,15]. With a lower radiation dose, high-performance MDCT methods have also become an optimal method for assessing LV function after AMI and ischemia-reperfusion [27–29].…”

Section: Discussionsupporting

confidence: 53%

“…In 2015, advances in imaging resulted in the introduction of third-generation DSCT that offered the availability of a complete evaluation of the morphology of the left ventricle (LV) and global cardiac function [14,15]. The associated reduction in the use of contrast agents and the reduction in radiation dose further expanded the clinical application of CT cardiac imaging [16].…”

Section: Introductionmentioning

confidence: 99%

“…The associated reduction in the use of contrast agents and the reduction in radiation dose further expanded the clinical application of CT cardiac imaging [16]. Recent meta-analysis data showed that cardiac CT provided an accurate assessment of global LV function and LV wall motion deficits, but the limits of agreement compared with cardiac MRI were moderately wide [15]. Therefore, cardiac CT provides a one-stop non-invasive imaging technique to evaluate both the severity of coronary artery stenosis and the status of cardiac function.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

A Pilot Study of Third-Generation Dual-Source Computed Tomography for the Assessment of Global Dynamic Changes in Left Ventricular Structure and Function in a Porcine Model of Acute Myocardial Infarction

Lyu

Yang

et al. 2019

Med Sci Monit

View full text Add to dashboard Cite

BackgroundFirst-generation and second-generation dual-source computed tomography (DSCT) are useful for analyzing left ventricle (LV) structure and function. This pilot study aimed to investigate the feasibility and role of third-generation DSCT for the evaluation of dynamic changes in LV structural and functional characteristics in a Diannan small-ear pig model of acute myocardial infarction (AMI).Material/MethodsThe model of AMI was established by balloon occlusion of the distal third of the left anterior descending (LAD) coronary artery in 14 Diannan small-eared pigs. Third-generation DSCT was performed to observe dynamic changes in LV structure and function before and after AMI was induced, with a follow-up period of 30 days.ResultsThe mean structural measurements at baseline included interventricular septum thickness (8.50±0.90 mm), LV anterior wall thickness (8.40±1.30 mm), LV posterior wall thickness (7.80±1.20 mm), LV end-diastolic dimension (LVEDD) (45.00±4.90 mm), and LV end-systolic dimension (LVESD) (25.90±4.10 mm). The mean functional measurements at baseline included the LV end-diastolic volume (LVEDV) (74.62±13.54 ml), LV end-systolic volume (LVESV) (23.06±7.46 ml), LV ejection fraction (LVEF) (69.29±6.83%), LV mass (86.35±14.02 g), stroke volume (SV) (51.56±9.77 ml), and cardiac output (CO) (4.22±2.14 l/min). Trends of time-dependent changes were observed for LVESV, LVEF, SV, and CO, but not for LVEDV or LV mass.ConclusionsThird-generation DSCT was validated as a tool for assessing dynamic changes in LV global function in a porcine model of AMI.

show abstract

Section: Discussionsupporting

confidence: 53%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

A Pilot Study of Third-Generation Dual-Source Computed Tomography for the Assessment of Global Dynamic Changes in Left Ventricular Structure and Function in a Porcine Model of Acute Myocardial Infarction

Lyu

Yang

et al. 2019

Med Sci Monit

View full text Add to dashboard Cite

show abstract

“…Recently, ECG-gated acquisition of cardiac 4DCT enables the combined assessment of coronary anatomy and LV function (7,8). Recent publications show that regional WMA detection with CT agrees with echocardiography (9, 10) as well as with cardiac magnetic resonance (11,12).…”

Section: Introductionmentioning

confidence: 96%

Detection of left ventricular wall motion abnormalities from volume rendering of 4DCT cardiac angiograms using deep learning

Chen

Contijoch

Colvert

et al. 2022

Front. Cardiovasc. Med.

View full text Add to dashboard Cite

BackgroundThe presence of left ventricular (LV) wall motion abnormalities (WMA) is an independent indicator of adverse cardiovascular events in patients with cardiovascular diseases. We develop and evaluate the ability to detect cardiac wall motion abnormalities (WMA) from dynamic volume renderings (VR) of clinical 4D computed tomography (CT) angiograms using a deep learning (DL) framework.MethodsThree hundred forty-three ECG-gated cardiac 4DCT studies (age: 61 ± 15, 60.1% male) were retrospectively evaluated. Volume-rendering videos of the LV blood pool were generated from 6 different perspectives (i.e., six views corresponding to every 60-degree rotation around the LV long axis); resulting in 2058 unique videos. Ground-truth WMA classification for each video was performed by evaluating the extent of impaired regional shortening visible (measured in the original 4DCT data). DL classification of each video for the presence of WMA was performed by first extracting image features frame-by-frame using a pre-trained Inception network and then evaluating the set of features using a long short-term memory network. Data were split into 60% for 5-fold cross-validation and 40% for testing.ResultsVolume rendering videos represent ~800-fold data compression of the 4DCT volumes. Per-video DL classification performance was high for both cross-validation (accuracy = 93.1%, sensitivity = 90.0% and specificity = 95.1%, κ: 0.86) and testing (90.9, 90.2, and 91.4% respectively, κ: 0.81). Per-study performance was also high (cross-validation: 93.7, 93.5, 93.8%, κ: 0.87; testing: 93.5, 91.9, 94.7%, κ: 0.87). By re-binning per-video results into the 6 regional views of the LV we showed DL was accurate (mean accuracy = 93.1 and 90.9% for cross-validation and testing cohort, respectively) for every region. DL classification strongly agreed (accuracy = 91.0%, κ: 0.81) with expert visual assessment.ConclusionsDynamic volume rendering of the LV blood pool combined with DL classification can accurately detect regional WMA from cardiac CT.

show abstract

“…For example, cardiac CT may be able to detect global left ventricular function and was able to assess cardiac wall motion abnormalities with a sensitivity of 90% and specificity of 97%. 5 Previous studies in this area have predicted that forced expiratory volume in 1 s (FEV1) correlated with mean lung density, although this was limited by the need to analyse the whole lung. 6 Other studies have been able to show that the transfer factor for the lung for carbon monoxide (TLCO) and FEV1 were able to correlate with volume of emphysema.…”

Section: Introductionmentioning

confidence: 99%

Textural analysis and lung function study: Predicting lung fitness for radiotherapy from a CT scan

et al. 2019

View full text Add to dashboard Cite

Objective: This study tested the hypothesis that shows advanced image analysis can differentiate fit and unfit patients for radical radiotherapy from standard radiotherapy planning imaging, when compared to formal lung function tests, FEV1 (forced expiratory volume in 1 s) and TLCO (transfer factor of carbon monoxide). Methods: An apical region of interest (ROI) of lung parenchyma was extracted from a standard radiotherapy planning CT scan. Software using a grey level co-occurrence matrix (GLCM) assigned an entropy score to each voxel, based on its similarity to the voxels around it. Results: Density and entropy scores were compared between a cohort of 29 fit patients (defined as FEV1 and TLCO above 50 % predicted value) and 32 unfit patients (FEV1 or TLCO below 50% predicted). Mean and median density and median entropy were significantly different between fit and unfit patients (p = 0.005, 0.0008 and 0.0418 respectively; two-sided Mann–Whitney test). Conclusion: Density and entropy assessment can differentiate between fit and unfit patients for radical radiotherapy, using standard CT imaging. Advances in knowledge: This study shows that a novel assessment can generate further data from standard CT imaging. These data could be combined with existing studies to form a multiorgan patient fitness assessment from a single CT scan.

show abstract

Noninvasive evaluation of global and regional left ventricular function using computed tomography and magnetic resonance imaging: a meta-analysis

Abstract: • CT helps to assess patients with coronary artery disease (CAD). • MRI is the reference standard for evaluation of left ventricular function. • CT provides accurate assessment of global left ventricular function.

Cited by 18 publications

References 86 publications

A Pilot Study of Third-Generation Dual-Source Computed Tomography for the Assessment of Global Dynamic Changes in Left Ventricular Structure and Function in a Porcine Model of Acute Myocardial Infarction

A Pilot Study of Third-Generation Dual-Source Computed Tomography for the Assessment of Global Dynamic Changes in Left Ventricular Structure and Function in a Porcine Model of Acute Myocardial Infarction

Detection of left ventricular wall motion abnormalities from volume rendering of 4DCT cardiac angiograms using deep learning

Textural analysis and lung function study: Predicting lung fitness for radiotherapy from a CT scan

Contact Info

Product

Resources

About