2020
DOI: 10.1109/tim.2019.2913612
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Noninvasive Estimation of Plasma Sodium Concentration During Hemodialysis via Capacitively Coupled Electrical Impedance Spectroscopy

Abstract: This paper presents a compact, low-cost, and noninvasive system for real-time estimation of plasma sodium concentration ([Na]Pl) during a hemodialysis (HD) session with state-of-the-art accuracy. It is based on electrical impedance spectroscopy (EIS) performed with a capacitively-coupled impedance sensing cell and a high-frequency measurement device, both custom-built. The EIS data are processed to infer the resistance of the liquid inside the cell, which is used together with an optical hemoglobin sensor to e… Show more

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Cited by 12 publications
(7 citation statements)
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“…There are several options for the choice of the pseudorandom wideband excitation sequence xn [41]. One possibility consists in randomly generating the elements π‘₯ 𝑛 ∈ {0,1}, with n=0,..,N-1, from a uniform binary discrete distribution and creating the cyclic inverse π‘₯ 𝑛 (𝑖𝑛𝑣) by implementing (5) in the discrete-time domain, which implies the off-line computation of the DFT and Inverse Discrete Fourier Transform (IDFT). This approach simplifies the signal generation circuit, which can be reduced to a simple 1-bit digital-to-analog converter (DAC) or even a digital output but requires to store in the memory of the embedded system both the sequences xn and π‘₯ 𝑛 (𝑖𝑛𝑣) , which could be an issue as long as the memory space is a limited resource.…”
Section: Generation Of the Pseudo-random Excitationmentioning
confidence: 99%
See 1 more Smart Citation
“…There are several options for the choice of the pseudorandom wideband excitation sequence xn [41]. One possibility consists in randomly generating the elements π‘₯ 𝑛 ∈ {0,1}, with n=0,..,N-1, from a uniform binary discrete distribution and creating the cyclic inverse π‘₯ 𝑛 (𝑖𝑛𝑣) by implementing (5) in the discrete-time domain, which implies the off-line computation of the DFT and Inverse Discrete Fourier Transform (IDFT). This approach simplifies the signal generation circuit, which can be reduced to a simple 1-bit digital-to-analog converter (DAC) or even a digital output but requires to store in the memory of the embedded system both the sequences xn and π‘₯ 𝑛 (𝑖𝑛𝑣) , which could be an issue as long as the memory space is a limited resource.…”
Section: Generation Of the Pseudo-random Excitationmentioning
confidence: 99%
“…It consists of a generic AFE, whose description is out of the scope of this manuscript (e.g. we can use the AFE presented in [5] or [29]), analog/digital interfaces, and a ULP digital platform on which both algorithms are implemented. We chose GAP-8 System-onchip as the energy efficient digital platform.…”
Section: Hardware Architecturementioning
confidence: 99%
“…M EASURING frequency response functions (FRF) is a first step towards the (physical) understanding of the dynamic behavior of real-life systems. Practical applications can be found in many disciplines of engineering and (bio-medical) sciences such as, vibration analysis of mechanical and civil engineering structures [1], [2], state-of-health monitoring of lithium-ion batteries [3], hemodialysis measurements [4], characterization of vegetable tissues [5], . .…”
Section: Introductionmentioning
confidence: 99%
“…The latter system consists in exciting the battery by using a narrowband signal and spanning the center frequency of this excitation. The narrowband measurement system is intrinsically slower but with superior resolution [8], [9], [10]. Most EIS instruments are benchtop devices and cannot be applied directly on the field to characterize batteries while they are operating.…”
Section: Introductionmentioning
confidence: 99%