Noninvasive central pulse pressure is an independent determinant of renal function

Xiao, Wenkai; Wang, Fan; Cao, Ruihua; Yang, Bai; Wang, Hongmei

doi:10.1111/jch.13792

Cited by 8 publications

(11 citation statements)

References 42 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…[25][26][27] Increased CPP leads to greater strain on the arterial vasculature, which increases arterial wall tension and predisposes elastic fibers to fatigue and fracture, as well as vascular endothelial cell damage, thereby promoting or accelerating the development and progression of atherosclerosis. [28,29] The results of this study showed an increasing trend of CSP and a decreasing trend of CDP with the increase in the number of branches of coronary lesions; however, neither of these reached statistical significance, which may be related to the small number of patients in this study. In contrast, the CPP of the multi-branch lesion group was significantly higher than that of the double-and single-branch lesion groups, which is consistent with the results of Kim et al, [30] indicating that CPP is clinically important for assessing the severity of coronary lesions.…”

Section: Discussioncontrasting

confidence: 65%

Correlation analysis of central arterial pressure parameters and the severity of atherosclerotic lesions in coronary arteries: A retrospective study

Fang,

Huang,

Liu

et al. 2023

Medicine

View full text Add to dashboard Cite

To investigate the correlation between central arterial pressure (CAP) parameters and the severity of atherosclerotic lesions in the coronary arteries, understand the value of CAP in assessing the risk of coronary heart disease (CHD), and provide a theoretical basis for the prevention and treatment of CHD. Between January 2021 and January 2022, 224 patients admitted to our hospital for complete coronary angiography (CAG) were included in this retrospective study. CAP parameters, including central systolic pressure (CSP), diastolic pressure (CDP), and pulse pressure (CPP), and Gensini scores were collected; the association between CAP parameters and the severity of coronary lesions was analyzed using the Pearson correlation coefficient (r) and multivariate regression analysis. CPP was significantly higher in the coronary multi-branch lesion group than in the single-branch lesion group in patients with CHD (P < .05). CSP, CDP, and CPP were significantly higher in the high Gensini score group than in the low Gensini score group for coronary vascular lesions; furthermore, CSP and CPP were significantly higher in the high Gensini score group than in the medium Gensini score group (P < .05). Pearson correlation analysis showed that CSP and CPP were positively and CDP was negatively correlated with the severity of coronary artery lesions in patients with CHD (P < .05). Logistic regression analysis showed that a history of diabetes, CSP, CDP, and CPP were independent risk factors for severe atherosclerotic lesions in the coronary arteries (P < .05). noninvasive CAP-related indices, such as CSP, CDP, and CPP, are independently correlated with and can be used to predict the severity of coronary lesions in patients with CHD, which may be beneficial for guiding clinical diagnosis and treatment.

show abstract

Section: Discussioncontrasting

confidence: 65%

Correlation analysis of central arterial pressure parameters and the severity of atherosclerotic lesions in coronary arteries: A retrospective study

Fang,

Huang,

Liu

et al. 2023

Medicine

View full text Add to dashboard Cite

show abstract

“… 22 A community‐based cohort study included 1426 participants, followed for a median of 4.8 years and found that central pulse pressure is an independent determinant of renal function. 23 And previous study have demonstrated that high resting heart rate is a potent predictor of renal outcomes. 24 However, there is no prospective data confirming whether pulsatile stress (the combined effect of the two components) in early life affect renal function in middle age.…”

Section: Discussionmentioning

confidence: 99%

Association of pulsatile stress in childhood with subclinical renal damage in adults: A 30‐year prospective cohort study

Liao

Chu

Wang

et al. 2021

J of Clinical Hypertension

View full text Add to dashboard Cite

The pulsatile stress in the microcirculation may contribute to development or progression of chronic kidney disease. However, there is no prospective data confirming whether pulsatile stress in early life affect renal function in middle age. The authors performed a longitudinal analysis of 1738 participants aged 6-15 years at baseline, an ongoing Adolescent Prospective Cohort with a follow-up of 30 years. The authors evaluated the association between pulsatile stress in childhood and adult subclinical renal damage (SRD), adjusting for related covariates. Pulsatile stress was calculated as resting heart rate × pulse pressure. Renal function was assessed with estimated glomerular filtration rate (eGFR) and urine albumin-to-creatinine ratio (uACR). The results showed that pulsatile stress in childhood was associated with adult SRD (Relative Risk, 1.43; p = .032), and the predictive value of combined pulse pressure and heart rate for SRD was higher than either of them alone. The high pulsatile stress in childhood increased the risk of adult SRD in males (RR, 1.92; p = .003), but this association was not found in females (RR, 0.91; p = .729). Further, the participants were categorized into four groups on the basis of pulsatile stress status in childhood and adulthood. Male patients with high pulsatile stress during childhood but normal pulsatile stress as adults still had an increased risk of SRD (RR, 2.04; 95% CI, 1.18-3.54), while female patients did not (RR, 0.96; 95% CI, 0.46-1.99). The study demonstrated that high pulsatile stress in childhood significantly increased the risk of adult SRD, especially in males. Adequate control of pulse pressure and heart rate from childhood, in the long-term, is very important for preventing kidney damage.

show abstract

“…(24)(25)(26) Therefore, PP might constitute a noninvasive proxy indicator for the decline of renal function. (27) The study employed a cross-sectional survey, making it difficult to establish a cause-and-effect relationship between associated factors and decline of renal function. According to secondary data used for analysis, some variables were incomplete.…”

Section: Discussionmentioning

confidence: 99%

Prevalence and Associated Factors in the Decline of Renal Function Among Outpatients Attending a Community Hospital, Central Thailand

Chamnanmont¹,

Chaiyakham²,

Kaensingh³

et al. 2021

J Southeast Asian Med Res

View full text Add to dashboard Cite

Introduction: Chronic kidney disease (CKD) is recognized as global public health issue especially affecting developing countries including Thailand. The epidemiologic data in the decline of renal function and the risk factors among Thai patients especially in community hospital settings were limited. Methods: A cross-sectional study was conducted to identify the prevalence and associated risk factors in the decline of renal function among outpatients in Thaluang Community Hospital, Lop Buri Province, central Thailand, between November 1, 2018 and October 31, 2019. The decline in renal function was defined by glomerular filtration rate (GFR) <60 mL/min/1.73m2. Multivariate logistic regression analysis was performed to obtain the adjusted odds ratios (AOR) and 95% confidence interval (CI) of the factors related to the decline of renal function. Results: A total of 874 outpatients participated in the study. The overall prevalence in the decline of renal function (eGFR <60 mL/min/1.73m2) was 20.3% (95% CI; 17.5%-22.9%). Among male participants, the prevalence in the decline of renal function was 21.1% (95%CI; 16.7%-25.5%) while it totaled 19.7% (95%CI; 16.3%-23.1%) among females. The independent associated factors in the decline of renal function included greater age (AOR 1.07; 95% CI=1.05-1.09), history of NSAIDs used (AOR 2.97; 95% CI=1.85-4.79) and elevated pulse pressure (PP) >75th percentile (AOR 1.64; 95% CI=1.07-2.53) Conclusion: We reported the prevalence in the decline of renal function among outpatients in a Thai community hospital which was comparable with the national level. Advanced age, history of NSAIDs used and PP were related to reduced kidney function. Therefore, effective health interventions should be conducted especially, appropriate NSAIDs used among outpatients.

show abstract

Noninvasive central pulse pressure is an independent determinant of renal function

Cited by 8 publications

References 42 publications

Correlation analysis of central arterial pressure parameters and the severity of atherosclerotic lesions in coronary arteries: A retrospective study

Correlation analysis of central arterial pressure parameters and the severity of atherosclerotic lesions in coronary arteries: A retrospective study

Association of pulsatile stress in childhood with subclinical renal damage in adults: A 30‐year prospective cohort study

Prevalence and Associated Factors in the Decline of Renal Function Among Outpatients Attending a Community Hospital, Central Thailand

Contact Info

Product

Resources

About