Prevalence and Associated Factors in the Decline of Renal Function Among Outpatients Attending a Community Hospital, Central Thailand

Chamnanmont, Chatchaya; Chaiyakham, Napat; Kaensingh, Sittirat; Kaewput, Wisit; Rangsin, Ram; Sakboonyarat, Boonsub

doi:10.55374/jseamed.v5i2.90

Cited by 3 publications

(4 citation statements)

References 26 publications

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“…The results of this study agreed with that of Chamnanmont et al (26) investigating the prevalence and associated factors for the decline of eGFR among patients attending a community hospital and reported the incidence of eGFR<60 mL/min/1.73m 2 was 20.3%; risk factors included age, NSAIDs use and presenting high blood pressure.…”

Section: /11 Journal Of Southeast Asian Medical Research E0153supporting

confidence: 91%

“…On the other hand, among patients with atrial fibrillation, studies compared the effects of nonvitamin K antagonist oral anticoagulant (NOAC) and warfarin; NOAC provided more reno-protective effects than warfarin. (24)(25)(26) Therefore, further investigation regarding drug use is crucial for establishing a solid conclusion.…”

Section: Discussionmentioning

confidence: 99%

“…Morbidity and mortality could possibly be reduced long term if we focused on blood pressure control among patients receiving an early diagnosis of hypertension. (26) This study encountered limitations. Proteinuria data was not included as one of the variables; proteinuria could be a mediator or extraneous variable and used as the main predictor for poor prognosis and increasing rate of kidney function decline.…”

Section: /11 Journal Of Southeast Asian Medical Research E0153mentioning

confidence: 92%

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The INCIDENCE AND RISK FACTORS FOR RAPID DECLINE OF PRESERVED ESTIMATED GLOMERULAR FILTRATION RATE AMONG PATIENTS WITH HYPERTENSION IN A COMMUNITY HOSPITAL

Thiannitiworakun,

Norraratputti,

Chantarapitak

et al. 2023

J Southeast Asian Med Res

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Background: Hypertension is the second most common leading cause of chronic kidney disease. Related studies explored the causes of the rapid decline of kidney function in advanced kidney disease. However, the causes of the rapid decline of kidney function in the early stage or preserved function of hypertensionrelated kidney disease are less evident. Objectives: The study aimed to identify the incidence and associated risk factors for the decline of the glomerular filtration rate (GFR) among patients with hypertension with preserved kidney function, estimated GFR (eGFR) above 60/mL/min/1.73m2, at a community hospital. Methods: A retrospective cohort study was conducted among patients with hypertension with 2 eGFR measures at least 1 year apart and were identified from all cases attending at the Outpatient Department, Sanam Chai Khet Hospital, Chachoengsao Province. The incidence of the estimated rate of eGFR decline greater than 5 mL/min/1.73m2 yearly (ERGFR5/yr) was determined. In addition, potential risk and protective factors were identified using Poisson Regression. Results: Of 1,328 patients with hypertension, 53.05% were females. The mean age was 59.68 ± 11.58 years. The mean GFR measure at the 1st visit was 88.71± 14.73 mL/min/1.73m2. The incidence of ERGFR5/yr was 11.1 (95% CI: 10.1-12.3)) per 100-person year. Risk factors were being 60 years or older with an incidence rate ratio (IRR) of 1.4 (95% CI: 1.11-1.77), having diabetes mellitus with an IRR of 1.67 (95% CI: 1.37-2.04) and uncontrolled hypertension with an IRR of 1.15 (95% CI: 1.10-1.20). Conclusion: The incidence of ERGFR5/yr among renal preserved patients with hypertension was relatively low compared with other studies. Aggressive intervention among patients with comorbidity could reduce the incidence of rapid decline in eGFR.

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Section: /11 Journal Of Southeast Asian Medical Research E0153supporting

confidence: 91%

Section: Discussionmentioning

confidence: 99%

Section: /11 Journal Of Southeast Asian Medical Research E0153mentioning

confidence: 92%

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The INCIDENCE AND RISK FACTORS FOR RAPID DECLINE OF PRESERVED ESTIMATED GLOMERULAR FILTRATION RATE AMONG PATIENTS WITH HYPERTENSION IN A COMMUNITY HOSPITAL

Thiannitiworakun,

Norraratputti,

Chantarapitak

et al. 2023

J Southeast Asian Med Res

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“…Similarly, in Thailand, the National Health Examination Survey VI in 2019 demonstrated that 25% of Thai adults aged ≥ 15 years suffer from hypertension (HT) [2]. Raised BP is a leading cause of end-organ damage, including ischemic heart disease, stroke, and chronic kidney disease [3][4][5][6][7]. Furthermore, a few studies reported the relationship between HT and liver dysfunction [8,9].…”

Section: Introductionmentioning

confidence: 99%

Association between raised blood pressure and elevated serum liver enzymes among active-duty Royal Thai Army personnel in Thailand

Sakboonyarat

Poovieng

Lertsakulbunlue

et al. 2023

BMC Cardiovasc Disord

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Background The relationship between hypertension (HT) and serum liver enzymes was reported in a few studies, but the findings were inconsistent. Therefore, the present study aimed to identify the association between elevated serum liver enzymes and raised BP through the use of a large sample of Royal Thai Army (RTA) personnel. Methods The dataset obtained from the annual health examination database of RTA personnel in Thailand was utilized. A total of 244,281 RTA personnel aged 35–60 were included in the current study. Elevated serum liver enzymes were defined as aspartate aminotransferase (AST) or alanine aminotransferase (ALT) ≥ 40 U/L in males and ≥ 35 U/L in females. HT was defined as systolic BP ≥ 140 or diastolic BP ≥ 90 mmHg. A multivariable linear regression model was used to estimate the coefficient and 95% confidence intervals (CI), whereas a multivariable logistic regression model was applied to estimate adjusted odds ratios (AORs) and 95% CI for the association between raised BP and serum liver enzymes. Results Compared to individuals with SBP < 120 and DBP < 80 mmHg, the β coefficients of log-transformed AST and ALT were 0.13 (95% CI: 0.12–0.13) and 0.11 (95% CI: 0.11–0.12) in males with HT. Meanwhile, the β coefficients of log-transformed AST and ALT were 0.03 (95% CI: 0.02–0.04) and 0.07 (95% CI: 0.05–0.08) in females with HT. In males, HT was associated with elevated AST (AOR: 1.92; 95% CI: 1.85–2.01) and elevated ALT (AOR: 1.43; 95% CI: 1.38–1.48). On the other hand, in females, HT was associated with elevated AST (AOR: 1.42; 95% CI: 1.21–1.66) and elevated ALT (AOR: 1.38; 95% CI: 1.21–1.57). Conclusion Raised BP was positively correlated with elevated AST and ALT in active-duty RTA personnel. Moreover, HT was independently attributed to higher odds of elevated AST and ALT in comparison to optimal BP in both males and females. Furthermore, the relationship between serum liver enzymes and BP was modified by sex.

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Chronic Kidney Disease and Accelerated Decline of Renal Function in Older Adults with HIV in Northern Thailand

Aurpibul

Parklak

Taejaroenkul

et al. 2023

AIDS Research and Human Retroviruses

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Prevalence and Associated Factors in the Decline of Renal Function Among Outpatients Attending a Community Hospital, Central Thailand

Cited by 3 publications

References 26 publications

The INCIDENCE AND RISK FACTORS FOR RAPID DECLINE OF PRESERVED ESTIMATED GLOMERULAR FILTRATION RATE AMONG PATIENTS WITH HYPERTENSION IN A COMMUNITY HOSPITAL

The INCIDENCE AND RISK FACTORS FOR RAPID DECLINE OF PRESERVED ESTIMATED GLOMERULAR FILTRATION RATE AMONG PATIENTS WITH HYPERTENSION IN A COMMUNITY HOSPITAL

Association between raised blood pressure and elevated serum liver enzymes among active-duty Royal Thai Army personnel in Thailand

Chronic Kidney Disease and Accelerated Decline of Renal Function in Older Adults with HIV in Northern Thailand

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