Noninvasive and real‐time in vivo characterization of Inflammation skin. A feasibility of animal study

Abstract

Skin, the largest and outermost organ of the body, mainly consisted dermis and epidermis, which provide a barrier function to protect the body from external stimuli and to prevent the loss of moisture from the body. [1][2][3][4] Skin and skin-related diseases, causing a global health burden, have become an international health issues whereas the inflammatory skin diseases were the most common problem in dermatology. The skin inflammation was usually accompanied with erythema and edema in the affected skin area, 5 and tissue destruction could even occur in chronic skin inflammation. 6 The skin inflammation, like erythema and edema, was usually and clinically evaluated by physician's naked-eye first, and such subjective evaluation was very dependent on their experience. Patient epidermal tissue section test, that is, skin biopsy test, might sometimes be required. Although the skin biopsy was still the gold standard for most dermatological diagnosis, it was invasive, and thereby leading to pain and scar

Bioimpedance-Measurement-Based Non-Invasive Method for In Ovo Chicken Egg Sexing

“…The concept of self-normalization, as introduced in Phan et al (2021) [ 15 ], was utilized to investigate the parameter affected by noise in the spectrum and to minimize the impact of variations between different embryos during data analysis.…”

“…Impedance spectroscopy is a well-established method for a variety of applications, including bacterial detection, biomarker detection, and microorganism viability determination [ 14 , 15 , 16 , 17 , 18 , 19 ]. The principle of this technique is to inject a constant current into the object to be measured and calculate its voltage to find out the electrical impedance response of the object.…”