Nonelectrolytes

Cockrill, J. R.

doi:10.1001/archneurpsyc.1931.02230060141007

Cited by 16 publications

(1 citation statement)

References 12 publications

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“…Thus, Myers & Fine (1919), Cockrill (1931), Leopold &Bernhard (1917) andFremont-Smith, Dailey, Merritt, Carroll &Thomas (1931), reported that the concentration of urea in the cerebrospinal fluid was lower than that of the plasma, and Ralls (1943) found a lower concentration in the blood cells. The concentration of urea in gastric juice is also lower than that in the plasma (Kornberg et al 1954).…”

Section: Discussionmentioning

confidence: 98%

The breakdown of urea in cats not secreting gastric juice

Kornberg¹,

Davies²,

Wood³

1954

Biochemical Journal

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Roberts &; Whelan (1951) have shown that this enzyme, when purified, has no action on maltose.We are not at this stage particularly concemed with differences between 'caries active' and 'caries inactive' groups of subjects. We also realize that the present DMF number is not necessarily an indication of the present caries activity. Nevertheless, certain interesting observations can be made. In group I (low DMF) fructose is metabolized at a significantly lower rate than any of the other sugars. There are also significant differences in the rates of oxidation of maltose and sucrose, and of maltose and glucose. There is no such difference in the case of glucose and sucrose. In group II (high DMF) the only conclusion which can be drawn is that fructose is metabolized at a lesser rate than the other three sugars. Our results therefore suggest that the pattern of utilization of different sugars by group I subjects differs from that of group II subjects. It is, however, unwise to deduce more from these observations on so few subjects. SUMMARY 1. The salivary flora metabolize fructose at a significantly lower rate than glucose, maltose, or sucrose.2. Subjects with a comparatively low DMF number (number of teeth decayed, missing or filled) also show differences in oxidation rate between glucose and maltose, and between sucrose and maltose, but not between sucrose and glucose.3. Subjects with a high DMF number did not show the differences enumerated in paragraph 2.Although Luck (1924a, b) had shown urease to be present in the stomachs of a wide variety of animals, urea was until recently regarded as solely an endproduct of mammalian nitrogen metabolism.

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Section: Discussionmentioning

confidence: 98%