Non-traumatic corneal perforations: aetiology, treatment and outcomes

Abstract

Corneal perforations represent an important cause of ocular morbidity. The use of a cyanoacrylate patch is useful as an initial therapy in corneal perforations; however, procedures such as PK are often necessary to achieve anatomical success, especially in non-infectious aetiologies.

Corneal Perforation Self-Healing with an Iris Plug in the Cornea

“…Due to lack of material, surgical management was not possible. Loya-Garcia et al [5] provide research advice to solve this kind of emergency as soon as possible, in order to delay further necessary procedures and earn some time. As the size of perforation was small, a simple bandage contact lens was sufficient to reconstitute the globe.…”

Treatment of a Perforated Corneal Ulcer with Tectonic DSAEK: a Case Report

“…mellar keratoplasty and perforating keratoplasty [3]. Tissue glues may be effective in some cases to solve the emergency and to delay other procedures [4]. When the corneal perforation is larger in size, involving the corneal periphery, the treatment options are limited to tectonic grafts [3,5].…”

Emergency penetrating keratoplasty in corneal perforations

“…Considering that emergency keratoplasty is a high risk procedure, a multitude of complications are possible: persistent epithelial defects, recurrence of corneal melting, graft rejection, late graft failure, recurrence of infection, glaucoma, cataract, persistent anterior chamber leakage, ingrowth of corneal and conjunctival epithelium, inflammatory membranes, retinal or choroidal detachment, endophthalmitis, or phthisis bulbi [ 9 , 11 , 15 , 18 ].…”

“…Usually, inflammatory conditions, such as collagen vascular diseases (i.e. rheumatoid arthritis [ 11 ]), Wegener’s granulomatosis, and Mooren’s ulcer are responsible for peripheral perforations, and occasionally can cause central ulceration, followed by perforation [ 14 ].…”