Non-surgical treatment as an alternative for the management of central giant cell granuloma: a systematic review

Camarini, Camila; Tolentino, Elen de Souza

doi:10.1007/s00784-021-04193-z

Cited by 4 publications

(1 citation statement)

References 43 publications

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“…The medical treatment included for this lesion mainly involves pharmacology applied directly into the lesion; intralesional corticosteroid has been used as well, showing variability in the long-term follow up [ 14 , 15 , 16 ]. Denosumab and immunotherapy have been used as neoadjuvants for these cases [ 17 ].…”

Section: Discussionmentioning

confidence: 99%

Central Giant Cell Granuloma in the Mandibular Condyle in a Teenager. A Case Report with Literature Review

Cantanhede

Olate

Assis³

et al. 2022

JCM

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Central giant cell granulomas (CGCG) are not common in the mandibular condyle. In teenagers, the problem is more complex because of difficulties in diagnosis and treatment involving the potential growth of the mandibular process and development of the face. In this short communication a case is presented of an eleven-year-old female under diagnosis of central giant cell granuloma affecting the mandibular condyle treated surgically in two steps using a condylectomy and vertical ramus osteotomy at the first time and later orthognathic surgery, showing the clinical evolution after 13 years of follow-up. In addition, we performed a review of the scientific reports related to CGCG in the mandibular condyle to compare this treatment with others, in terms of follow-up and results. We concluded that the CGCG affecting the mandibular head can be properly treated with low condilectomy, vertical mandibular ramus sliding osteotomy, and discopexy.

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Section: Discussionmentioning

confidence: 99%

Central Giant Cell Granuloma in the Mandibular Condyle in a Teenager. A Case Report with Literature Review

Cantanhede

Olate

Assis³

et al. 2022

JCM

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Multiple central giant cell granuloma of the jaws: diagnostic signposts of Noonan syndrome and RASopathy

Friedrich,

Rutkowski,

Gosau

2024

Oral Maxillofac Surg

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Noonan syndrome (NS) is a phenotypically variable inherited multi-system disorder. Maxillofacial findings can be diagnostic, especially in the evaluation of discrete facial dysmorphia. Diagnostic landmark findings of therapeutic relevance for the jaws such as central giant cell granuloma (CGCG) are rare in NS. However, recent molecular genetic studies indicate that these rare, benign lesions are neoplasms and more common in specific syndromes grouped under the umbrella term RASopathies. A specialist surgical diagnosis can be helpful in identifying the underlying disease. This report outlines diagnosis and treatment of a case of CGCG for which jaw diagnosis became the key to identifying a syndromic disease.

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Denosumab as treatment of central giant cell granuloma of the jaws. a scoping review

Latorre,

Atalah,

Marshall Baburizza

2024

Oral Maxillofac Surg

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Non-surgical treatment as an alternative for the management of central giant cell granuloma: a systematic review

Cited by 4 publications

References 43 publications

Central Giant Cell Granuloma in the Mandibular Condyle in a Teenager. A Case Report with Literature Review

Central Giant Cell Granuloma in the Mandibular Condyle in a Teenager. A Case Report with Literature Review

Multiple central giant cell granuloma of the jaws: diagnostic signposts of Noonan syndrome and RASopathy

Denosumab as treatment of central giant cell granuloma of the jaws. a scoping review

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