Non‐segmental vitiligo and psoriasis comorbidity – a case‐control study in Italian patients

Arunachalam, Meena; Dragoni, Federica; Colucci, Roberta; Berti, Samantha; Crocetti, Emanuele; Galeone, M; Conti, Rena M.; Moretti, Silvia

doi:10.1111/jdv.12117

Cited by 25 publications

(16 citation statements)

References 27 publications

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“…The choice of surgery, which depends upon ‘remote’ melanocytes, is the third possible option. Despite the fact that segmental vitiligo has a different story than non‐segmental vitiligo , the therapeutic plan proposed in the current viewpoint is applicable for segmental vitiligo, but with the urgency of early commencement of treatment. This is to avoid the entry in the ‘early’ leucotrichia phase that is one of the major clinical characteristics of segmental vitiligo patients , which would deem the loss of the source of the vertical melanocyte migration.…”

Section: The Personalized Options: Repigmentation/depigmentation/camomentioning

confidence: 99%

Beyond vitiligo guidelines: combined stratified/personalized approaches for the vitiligo patient

Anbar

Hegazy

Picardo

et al. 2014

Experimental Dermatology

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'Vitiligo' is a word that bears endless possibilities and no promises. Each vitiligo patient has a different story that demands a different therapeutic approach. Even though great efforts have been made to evaluate, study, compare and document the different therapeutic modalities available for vitiligo, clearly handling their modes of actions as well as their side effects and establishing clear stratified guidelines, numerous dilemmas are frequently met on practical grounds. 'Stabilize', 'repigment', 'depigment' or 'camouflage'? 'for whom and how do we achieve the best results' ? 'Separately or in combination ? -questions that need to be answered and decisions need to be taken in the appropriate timing and altered when the necessity arises. In the current viewpoint, we have utilized the available knowledge and exploited years of experience in an attempt to go beyond the guidelines to set the rationale for an optimal and personalized therapy, within the framework of a stratified approach.

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Section: The Personalized Options: Repigmentation/depigmentation/camomentioning

confidence: 99%

Beyond vitiligo guidelines: combined stratified/personalized approaches for the vitiligo patient

Anbar

Hegazy

Picardo

et al. 2014

Experimental Dermatology

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“…Psoriasis affects around 1–4.8% of the world population . Studies on the prevalence of psoriasis in vitiligo patients reveal contradicting results.…”

Section: Psoriasis and Vitiligomentioning

confidence: 99%

“…found concurrent vitiligo and psoriasis in 27 (6%) of the cases. Remarkably, the comorbidity of vitiligo and even mild psoriasis was associated with a family history of cardiovascular disease . In another study from Iran, 219 patients with psoriasis and 154 cases with vitiligo were investigated for the frequency of these two diseases simultaneously.…”

Section: Psoriasis and Vitiligomentioning

confidence: 99%

Comorbidities in vitiligo: comprehensive review

Dahir

Thomsen

2018

Int J Dermatology

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Vitiligo is a common skin disorder characterized by idiopathic, progressive cutaneous hypomelanosis. Vitiligo is associated with several comorbid autoimmune, systemic, and dermatological diseases, primarily thyroid disease, alopecia areata, diabetes mellitus, pernicious anemia, systemic lupus erythematosus, rheumatoid arthritis, Addison's disease, inflammatory bowel disease, Sjögren's syndrome, dermatomyositis, scleroderma, ocular and audiological abnormalities, psoriasis, and atopic dermatitis. It is essential to increase awareness of these comorbidities in order to improve the disease burden and quality of life of patients with vitiligo. Herein, we review the association with the most frequent comorbidities associated with vitiligo.

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“…Rheumatoid arthritis, multiple sclerosis, systemic lupus erythematosus, systemic sclerosis, psoriasis, and autoimmune thyroid diseases are some of the disorders linked to obesity and they can also be associated with vitiligo [5][6][7][8][9] .…”

Section: Introductionmentioning

confidence: 99%

No Association between Vitiligo and Obesity: A Case-Control Study

Dragoni¹,

Conti²,

Cazzaniga³

et al. 2017

Med Princ Pract

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Objective: The purpose of this study was to investigate the relationship between vitiligo and body mass index (BMI) to assess the possible association between vitiligo and obesity. Subjects and Methods: This was a case-control study on a total of 400 participants, i.e., 200 patients with vitiligo and 200 healthy volunteers. Medical assessments were performed by dermatologists using the modified Vitiligo European Task Force form. The height and weight of all of the participants were measured and used to calculate the BMI. Data were analyzed using multivariate logistic regression models. Adjustment for age and gender was carried out preliminarily in the case-control analysis, whereas a forward stepwise selection algorithm was used to assess which independent factors were associated with a BMI ≥30 or a BMI ≤18.5. Results: Comparison of the vitiligo and control groups revealed the absence of a significant association. The multivariate analysis of factors associated with a high BMI (≥30) in vitiligo patients showed a significant association between a high BMI and a sudden onset of vitiligo (p = 0.021; OR = 3.83; 95% CI 1.22-11.99) and the presence of inflammation and pruritus (p = 0.031; OR = 3.26; 95% CI 1.11-9.57). No significant association was observed in the analysis of factors associated with a low BMI (≤18.5) in vitiligo patients. Conclusion: In this study, vitiligo did not appear to be associated with a high BMI; obesity might not be a risk factor for vitiligo, in contrast to most autoimmune diseases which are significantly associated with obesity.

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Non‐segmental vitiligo and psoriasis comorbidity – a case‐control study in Italian patients

Abstract: The presence of vitiligo and even mild psoriasis is significantly correlated with a family history of cardiovascular disease, a factor that requires greater attention and follow-up with respect to that necessary for vitiligo patients.

Cited by 25 publications

References 27 publications

Beyond vitiligo guidelines: combined stratified/personalized approaches for the vitiligo patient

Beyond vitiligo guidelines: combined stratified/personalized approaches for the vitiligo patient

Comorbidities in vitiligo: comprehensive review

No Association between Vitiligo and Obesity: A Case-Control Study

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