Non-randomized comparative study of irradiation alone or in combination with surgery in stage Ib, Ha and “proximal” IIb carcinoma of the cervix

Bachaud, Jean-Marc; Fu, Ren Chuan; Delannes, M.; Izar, F.; Martel, P.; David, Jean-Marc; Shubinski, R; Daly, N; Montana, Gustavo S.

doi:10.1016/0167-8140(91)90005-2

Cited by 16 publications

(2 citation statements)

References 35 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Radiation therapy that is delivered by combining external beam radiotherapy (EBRT) and brachytherapy is a curative treatment option for uterine cervical cancer and is the standard therapy for a locally advanced disease [1,2,3,4,5,6,7,8,9]. Radiation therapy with a high-dose-rate (HDR) remote afterloading system for intracavitary brachytherapy is the standard treatment for uterine cervical cancer in Japan [10].…”

Section: Purposementioning

confidence: 99%

Assessment of the anatomical position of point B and the relationship between point B dose and the dose delivered to pelvic lymph nodes in CT-based high-dose-rate brachytherapy for uterine cervical cancer

Matsukawa

Sasaki

Hirayama

et al. 2019

jcb

View full text Add to dashboard Cite

Purpose To examine the anatomical position of point B and the relationship between the dose at point B and the dose delivered to the pelvic lymph nodes in computed tomography (CT)-based brachytherapy for cervical cancer. Material and methods Forty-nine cervical cancer patients were treated at Kyushu University Hospital. For all cases, planning CT images obtained after the applicator insertion were imported to an Oncentra Brachy (Elekta AB, Stockholm, Sweden), and points A (dose prescription, 6 Gy) and points B were set according to the Manchester method. The pelvic lymph node regions (external iliac, internal iliac, and obturator) were contoured, and the anatomic positions of 98 points B in 49 patients were examined. Dose volume histogram (DVH) parameters (D 100 , D 90 , D 50 , D 2cc , D 1cc , and D 0.1cc ) were calculated for each lymph node region and compared with the point B dose. Results The mean bilateral dose to point B was 1.70 ±0.18 Gy, and 26 (27%) of 98 points B were not located in any pelvic lymph node regions. The DVH analysis indicated a low degree of correlation overall, and all values were significantly different from point B doses ( p < 0.05), except for D 0.1cc of the external iliac node ( p = 0.0594) and D 1cc of the internal iliac node ( p = 0.0711). Conclusions We investigated the anatomical location of point B in patients with cervical cancer who underwent brachytherapy, and the DVH analysis revealed that the point B dose was a poor surrogate for the dose delivered to the pelvic lymph nodes.

show abstract

Section: Purposementioning

confidence: 99%

Assessment of the anatomical position of point B and the relationship between point B dose and the dose delivered to pelvic lymph nodes in CT-based high-dose-rate brachytherapy for uterine cervical cancer

Matsukawa

Sasaki

Hirayama

et al. 2019

jcb

View full text Add to dashboard Cite

show abstract

“…Radiation therapy (RT) is a proven curative therapy for cervical cancer and is the standard therapy for locally advanced disease (1)(2)(3)(4)(5)(6)(7). RT is most commonly and effectively delivered with a combination of external beam RT (EBRT) and brachytherapy (BT).…”

Section: Introductionmentioning

confidence: 99%