Non-Pharmacologic Management of Epilepsy

Parakh, Manish; Katewa, Vikash

doi:10.1007/s12098-014-1519-z

Cited by 8 publications

(16 citation statements)

References 51 publications

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“…In either case, when RTFM is performed, the ECoG signals recorded from the subdural grids (implanted as a part of standard presurgical evaluation for epilepsy surgery) (►Fig. 3) are separated into two streams: (1) video-ECoG monitoring for seizure localization and (2) for RTFM mapping. This is done to ensure that the recording of the ECoG signal for seizure monitoring remains uninterrupted.…”

Section: Real-time Functional Mapping-methodological Considerations Smentioning

confidence: 99%

“…1 Epilepsy surgery can provide with a successful treatment option for this patient population. 2,3 Successful seizure outcome depends on the surgeon's ability to remove the entire epileptogenic zone, which may overlap with important functional areas. 4 As a result, there is a strong need for precise cortical functional mapping to minimize functional deficits while eliminating seizure onset zone.…”

Section: Introductionmentioning

confidence: 99%

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Electrocorticography-Based Real-Time Functional Mapping for Pediatric Epilepsy Surgery

et al. 2015

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Precise localization of eloquent cortex in children may provide much needed surgical guidance and expand surgical epilepsy treatment options. It reduces the risk of postsurgical functional deficits and benefits children's quality of life, educational capacity, and long-term employment potential. The ultimate goal of functional mapping for pediatric epilepsy surgery is to decrease postsurgical functional morbidity. In this review article, we will discuss the electrocorticography (ECoG)-based real-time functional mapping (RTFM) technique for localizing motor-, somatosensory-, and language-specific regions. The examples demonstrating ECoG-based RTFM mapping techniques will be given from the data produced by the authors. We will demonstrate that the RTFM technique is a functional mapping tool based on direct measurement of neural activity that is time- and effort-effective, safe, well tolerated by children, and is expected to lead to reduced postsurgical functional morbidity in pediatric epilepsy patients. In conjunction with other utilized functional imaging modalities, RTFM may reduce cognitive morbidity and, as a consequence, benefit children's quality of life and educational capacity.

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Section: Real-time Functional Mapping-methodological Considerations Smentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Electrocorticography-Based Real-Time Functional Mapping for Pediatric Epilepsy Surgery

et al. 2015

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“…In contrast, nonpharmacological management of epilepsy sometimes has unexpected effects. These treatments can be divided into several categories, including the ketogenic diet and its modifications, epilepsy surgery, neurostimulation (vagus nerve stimulation, deep brain stimulation, responsive cortical neurostimulation, and transcranial magnetic stimulation) [ 176 , 177 ].…”

Section: Sleep and Anticonvulsant Therapymentioning

confidence: 99%

The Mutual Interaction Between Sleep and Epilepsy on the Neurobiological Basis and Therapy

Wang

Zhang

et al. 2017

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Background:Sleep and epilepsy are mutually related in a complex, bidirectional manner. However, our under-standing of this relationship remains unclear.Results:The literatures of the neurobiological basis of the interactions between sleep and epilepsy indicate that non rapid eye movement sleep and idiopathic generalized epilepsy share the same thalamocortical networks. Most of neurotransmitters and neuromodulators such as adenosine, melatonin, prostaglandin D2, serotonin, and histamine are found to regulate the sleep-wake behavior and also considered to have antiepilepsy effects; antiepileptic drugs, in turn, also have effects on sleep. Fur-thermore, many drugs that regulate the sleep-wake cycle can also serve as potential antiseizure agents. The nonpharmacologi-cal management of epilepsy including ketogenic diet, epilepsy surgery, neurostimulation can also influence sleep.Conclusion:In this paper, we address the issues involved in these phenomena and also discuss the various therapies used to modify them.

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“…De siste 20 årene har kirurgisk behandling av epilepsi fått økende betydning (Karl Otto Nakken, 2010). Men for de som ikke er aktuelle kandidater for epilepsikirurgi finnes det andre terapiformer, slik som vagusnervestimulator (VNS), dyp hjernestimulering (DBS), transkranial magnetstimulering og ketogen diett (Parakh & Katewa, 2014). VNS-terapi har i Norge vaert brukt i over 20 år, og er behandling med en implanterbar pulsgenerator med elektroder som stimulerer vagusnerven (Karl Otto Nakken, 2010).…”

Section: Introduksjonunclassified

Forbedring av rutiner rundt pasienter med vagusnervestimulator

Tørris¹,

Schøyen²,

Wiklund³

2015

NorTidHelse

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Improving routines for patients with vagus nerve stimulationBackground: Vagus Nerve Stimulator (VNS) is a form of therapy which may reduce the frequency of seizures in people with epilepsy, who do not achieve remission with antiepileptic drugs. A corresponding magnet providing an additional dose of stimulation may stop or shorten the intensity of the seizure.Objective Investigate the practice and procedure regarding use and storage of a VNS Therapy magnet, to see whether introduction of a new routine with a permanent seat for VNS magnet may contribute to increased availability of the magnet.Method Registration of the magnets location was performed before, and after the magnetic board intervention. In addition staff answered a questionnaire related to experiences around storage of magnet.Results The number of not located magnets dropped from 70% to 25 % after the intervention.Conclusion A magnetic board as a storage area for VNS magnet on the patient's room increases the availability of the magnet.

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Non-Pharmacologic Management of Epilepsy

Cited by 8 publications

References 51 publications

Electrocorticography-Based Real-Time Functional Mapping for Pediatric Epilepsy Surgery

Electrocorticography-Based Real-Time Functional Mapping for Pediatric Epilepsy Surgery

The Mutual Interaction Between Sleep and Epilepsy on the Neurobiological Basis and Therapy

Forbedring av rutiner rundt pasienter med vagusnervestimulator

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