Body height is a life-history component. it involves important costs for its expression and maintenance, which may originate trade-offs on other costly components such as reproduction or immunity. Although previous evidence has supported the idea that human height could be a sexually selected trait, the explanatory mechanisms that underlie this selection are poorly understood. Despite extensive studies on the association between height and attractiveness, the role of immunity in linking this relation is scarcely studied, particularly in non-Western populations. Here, we tested whether human height is related to health measured by self-perception, and relevant nutritional and health anthropometric indicators in three Latin-American populations that widely differ in socioeconomic and ecological conditions: two urbanised populations from Bogota (colombia) and Mexico city (Mexico), and one isolated indigenous population (Me'phaa, Mexico). Results showed that self-reported health is best predicted by an interaction between height and waist circumference: the presumed benefits of being taller are waist-dependent, and affect taller people more than shorter individuals. If health and genetic quality cues play an important role in human mate-choice, and height and waist interact to signal health, its evolutionary consequences, including cognitive and behavioural effects, should be addressed in future research. In modern Western societies, it has been seen that women usually prefer men who are significantly taller than average 1-3 , while men are more tolerant in choosing women who are taller or shorter than average 4. This is consistent with the idea that male height can be adaptive 5 and sexual selection favours taller men, possibly because height may represent an honest signal of individual quality, providing hereditary advantages, such as genetic quality for the offspring 6,7 , or direct benefits, provisioning resources and protection for women and their children 8. Following these last possible benefits, height has been also proposed as an indicator of resource holding potential (RHP), in terms of social dominance and deference 9,10 and socioeconomic status 6,11. This idea is supported by evidence that the male height is directly correlated with reproductive success, which is not applicable to women, suggesting an unrestricted directional selection that favours very tall men but not to very tall women 12. In fact, it has been reported that taller men (but not extremely tall men) are more likely to find a long-term partner and have several different long-term partners 13 , while the maximum reproductive success of women is below the female average height 14. Furthermore, heterosexual men and women tend to adjust their