Non‐invasive evaluation techniques to quantify the efficacy of cosmetic anti‐cellulite products¹

Abstract

Macrophotography and ultrasound imaging can be regarded as important tools for determining and quantifying the aspects of cellulite. With a gold standard missing for investigating cellulite severity, these two methods may not determine cellulite at the cellular level, but they do characterize the skin appearance so typical for cellulite. Combined with a variety of other methods, macrophotography and ultrasound imaging can very well define cellulite-reducing efficacy from the cosmetic point of view.

The High Frequency (HF) Ultrasound as a Useful Imaging Technique for the Efficacy Assessment of Different Anti-Cellulite Treatments

“…However, as these are relatively new scientific areas, the reliable research methodology has not been developed yet, which could provide for the objective verification of the administered treatments and performed procedures. The search for the non-invasive methods in order to monitor the treatment progress has been pending [4,9,12]. It is particularly im-portant to develop a method for the efficacy assessment of the applied treatments.…”

“…It affects approximately 85% -90% of female population and increasingly affects the male population, as well [7]. Until present, the stage of cellulite development has been usually assessed using palpation (and specifically developed scales), macrophotography or termography [4,[8][9][10]. The magnetic resonance imaging (MRI), computed tomography (CT) and ultrasound scanning were also tried [6,11,12].…”

Anticellulite efficacy of Trichilia catigua and Ptychopetalum olacoides Bentham extracts

“…Weight, height and circumference of some body areas [16] were assessed by qualified technicians. Body Mass Index (BMI) was calculated through the ratio mass/ height 2 and expressed in kg/m 2 .…”

“…O peso, altura e circunferência de algumas áreas do corpo [16] At the beginning of the study (D1), subjects remained in a room for 20 minute at 22 ± 2° C and relative humidity of 55 ± 5% for acclimatization. Afterward, they were taken to the evaluation room with identical environmental conditions.…”

Selüli̇tte Topi̇kal Yaklaşimlar

“…Selülitin giderilmesinde önem arz eden subkutan dokunun kalınlığının azalmasına yönelik belirleme, deriye ultrason uygulanması yani selülit ultrasonografisi ile yapılır. Bu amaçla formülasyonun/ürünün uygulanması kaynaklı hipodermis kalınlığındaki azalmanın tespiti için, başlangıçta ve kullanım süresince belirlenen zaman noktalarında yapılan deri ultrasonografisinden alınan hipodermis kalınlık değerleri ölçülür (36,37). Selülit giderici ve/veya azaltıcı formülasyonların veya ürünlerin etkinliğinin gönüllüler üzerinde denendiği çalışma sayısının oldukça az olduğu dikkat çekmektir.…”