Non-Invasive Biomechanical Evaluation of Implanted Human Cryopreserved Arterial Homografts

Bia, Daniel; Zócalo, Yanina; Armentano, Ricardo L.; Laza, Sebastián; Pérez, Héctor; Craiem, Damián; Saldías, María; Alvarez, I.

doi:10.1007/s10439-009-9693-2

Cited by 20 publications

(10 citation statements)

References 35 publications

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“…A video (cine-loop) of at least 10 seconds was recorded from each angle of interrogation. The CIMT and beat-to-beat diameter waveforms were obtained and analyzed off-line using a step-by-step border detection algorithm applied to each digitized image [12] (Figure 1(a)). A region 1.0 cm proximal to the carotid bulb was identified, and the far wall CIMT determined as the distance between the lumen-intima and the media-adventitia interfaces.…”

Section: Methodsmentioning

confidence: 99%

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Integrated Evaluation of Age-Related Changes in Structural and Functional Vascular Parameters Used to Assess Arterial Aging, Subclinical Atherosclerosis, and Cardiovascular Risk in Uruguayan Adults: CUiiDARTE Project

Bia¹,

Zócalo²,

Farro³

et al. 2011

International Journal of Hypertension

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This work was carried out in a Uruguayan (South American) population to characterize aging-associated physiological arterial changes. Parameters markers of subclinical atherosclerosis and that associate age-related changes were evaluated in healthy people. A conservative approach was used and people with nonphysiological and pathological conditions were excluded. Then, we excluded subjects with (a) cardiovascular (CV) symptoms, (b) CV disease, (c) diabetes mellitus or renal failure, and (d) traditional CV risk factors (other than age and gender). Subjects (n = 388) were submitted to non-invasive vascular studies (gold-standard techniques), to evaluate (1) common (CCA), internal, and external carotid plaque prevalence, (2) CCA intima-media thickness and diameter, (3) CCA stiffness (percentual pulsatility, compliance, distensibility, and stiffness index), (4) aortic stiffness (carotid-femoral pulse wave velocity), and (5) peripheral and central pressure wave-derived parameters. Age groups: ≤20, 21–30, 31–40, 41–50, 51–60, 61–70, and 71–80 years old. Age-related structural and functional vascular parameters profiles were obtained and analyzed considering data from other populations. The work has the strength of being the first, in Latin America, that uses an integrative approach to characterize vascular aging-related changes. Data could be used to define vascular aging and abnormal or disease-related changes.

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Section: Methodsmentioning

confidence: 99%

“…To this end, using mechanotransducers placed simultaneously on the skin over the carotid and femoral arteries (subjects in supine position), the carotid and femoral pulse waves were recorded [11, 12] (Figure 1(b)). Straight distance between the recording sites (car-fem distance) was measured (using a tape) on the body surface.…”

Section: Methodsmentioning

confidence: 99%

Integrated Evaluation of Age-Related Changes in Structural and Functional Vascular Parameters Used to Assess Arterial Aging, Subclinical Atherosclerosis, and Cardiovascular Risk in Uruguayan Adults: CUiiDARTE Project

Bia¹,

Zócalo²,

Farro³

et al. 2011

International Journal of Hypertension

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“…carotid artery dorsalis pedis pulse wave velocity (cdPWV) and carotid radial pulse wave velocity (crPWV)). cfPWV is recognized as the “gold standard” parameter for the evaluation of arterial stiffness and has had a wide biomedical application [[11],[12]]. The analysis of the peripheral pulse wave (cdPWV and crPWV) can provide parameters with different meanings in the arterial dynamics, some already used to assess the arterial stiffness [[13],[14]].…”

Section: Introductionmentioning

confidence: 99%

Neck circumference and early stage atherosclerosis: the cardiometabolic risk in Chinese (CRC) study

Liang

Wang

et al. 2014

Cardiovasc Diabetol

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BackgroundNeck circumference (NC) has been previously related to cardiometabolic risk factors. In this study we examined the association between NC and early stage atherosclerosis in Chinese adults.MethodsThe study samples were from a community-based health examination survey in central China. In total 2,318 men and women (18-64 y) were included in the final analyses. Carotid radial pulse wave velocity (crPWV), carotid femoral PWV (cfPWV), carotid artery dorsalis pedis PWV (cdPWV) and NC were measured.ResultsAfter adjustment for age, sex, lipids, glucose, blood pressure, heart rate, body mass index (BMI), high NC was significantly associated with an increasing trend of cfPWV, cdPWV and crPWV (P = 0.001, 0.049, and 0.038; respectively). In addition, we found significant interaction between hypertension status and NC level in relation to cfPWV, adjusted for age, sex, BMI, fasting glucose, lipids and heart rate(P for interaction = 0.034). The associations between NC and cfPWV were significant (P = 0.02) among those with hypertension, but not significant among those without hypertension.ConclusionsOur data showed that high NC was associated with an increased risk of early stage atherosclerosis in Chinese adults, independent of other metabolic risk factors. Hypertension might modify the association between NC and cfPWV.

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“…The carotid-brachial PWV is not a predictor of cardiovascular events, but it is a technique widely used to noninvasively characterize the upper limb arterial stiffness. PWV measurements were performed using two high-fidelity strain gauges mechanotransducers (Motorola MPX 2050, Motorola Inc., Corporate 1303 E. Algonquin Road, Schaumburg, IL 60196, USA) connected to an electronic signal amplifier device [17]. Both mechano-transducers were simultaneously positioned on the skin over the carotid-femoral or carotid-brachial arteries.…”

Section: Methodsmentioning

confidence: 99%

“…Furthermore, we have demonstrated that BM between an upper limb native artery and a vascular substitute can be minimized by selecting the most adequate type of vascular homograft [13]. Homografts have been used in by-pass and VA construction [14–17]; nonetheless, the selection of the most appropriate homograft capable to minimize the BM in CHP upper limbs should be evaluated, taking into account gender and previous vascular access placement.…”

Section: Introductionmentioning

confidence: 99%

Vascular Accesses for Haemodialysis in the Upper Arm Cause Greater Reduction in the Carotid-Brachial Stiffness than Those in the Forearm: Study of Gender Differences

Bia

Cabrera-Fischer

Galli

et al. 2012

International Journal of Nephrology

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Purpose. To evaluate in chronically haemodialysed patients (CHPs), if: (1) the vascular access (VA) position (upper arm or forearm) is associated with differential changes in upper limb arterial stiffness; (2) differences in arterial stiffness exist between genders associated with the VA; (3) the vascular substitute (VS) of choice, in biomechanical terms, depends on the previous VA location and CHP gender. Methods. 38 CHPs (18 males; VA in upper arm: 18) were studied. Left and right carotid-brachial pulse wave velocity (PWVc-b) was measured. In in vitro studies, PWV was obtained in ePTFE prostheses and in several arterial and venous homografts obtained from donors. The biomechanical mismatch (BM) between CHP native vessel (NV) and VS was calculated. Results/Conclusions. PWVc-b in upper limbs with VA was lower than in the intact contralateral limbs (P < 0.05), and differences were higher (P < 0.05) when the VA was performed in the upper arm. Differences between PWVc-b in upper limbs with VA (in the upper arm) with respect to intact upper limbs were higher (P < 0.05) in males. Independently of the region in which the VA was performed, the homograft that ensured the minimal BM was the brachial artery. The BM was highly dependent on gender and the location in the upper limb in which the VA was performed.

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Non-Invasive Biomechanical Evaluation of Implanted Human Cryopreserved Arterial Homografts

Cited by 20 publications

References 35 publications

Integrated Evaluation of Age-Related Changes in Structural and Functional Vascular Parameters Used to Assess Arterial Aging, Subclinical Atherosclerosis, and Cardiovascular Risk in Uruguayan Adults: CUiiDARTE Project

Integrated Evaluation of Age-Related Changes in Structural and Functional Vascular Parameters Used to Assess Arterial Aging, Subclinical Atherosclerosis, and Cardiovascular Risk in Uruguayan Adults: CUiiDARTE Project

Neck circumference and early stage atherosclerosis: the cardiometabolic risk in Chinese (CRC) study

Vascular Accesses for Haemodialysis in the Upper Arm Cause Greater Reduction in the Carotid-Brachial Stiffness than Those in the Forearm: Study of Gender Differences

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