Non-equilibrium thermodynamics of electrokinetic effects across mixed-lipid membranes

Studies on Electrokinetic Effects Across Supported Mixed Lipid Membranes

“…Across mixed lipids the permeability decreases in the order serine + lecithin > serine + inositol > serine + cephalin > lecithin + inositol > lecithin + cephalin > cephalin + inositol. Acetone permeates across mixed lipids in almost the same fashion as we found for water [6]. If the membrane matrix has two lipids, having different permeability values, then its permeability was found to be between the values of the permeabilities of the membranes heing coated with only one of the respective lipids.…”

“…The total weight of the two lipids always has been equal to that used for the incorporation of a single lipid [1]. The procedure adopted to deposit the lipids has been the same as described in [1,6]. The homogeneity of the lipid layer was ensured by telescopic examination.…”

Nonequilibrium Thermodynamics in Engineering and Science

“…Also a metabolic flux analysis combined with a metabolic control analysis has been used to quantify in vivo measurements of pathway fluxes in to and out of the cell and to identify the alternative pathways for the same chemical change . The flux control coefficients (FCC), C i , quantify the influence of individual reaction rates on the overall flux through the pathway.…”

“…The FCCs are related to the so-called elasticity coefficients through connectivity theorems where the elasticity coefficients are given by where x j is the concentration of the j th metabolite. The elasticity coefficients can be determined using the NET theory, in which the kinetics of enzyme reactions are described as linear functions of the change in Gibbs free energy of the reaction . For example, for a simple two-step pathway, the elasticity coefficients can be related to the affinity of the reactions as has been shown for the first two reactions in the penicillin biosynthetic pathway.…”

Nonequilibrium thermodynamics of membrane transport

“…There are many other phenomena dealing with membrane transport as discussed by De Groot (1961), De Groot andMazur (1962), Fitts (1962), and Kondepudi and Prigogine (1998), which are omitted here for the sake of brevity. Nonequilibrium thermodynamics of electrokinetic effects across mixed-lipid membranes is reported by Rizvi and Zaidi (1986). Transport through charged membranes was studied by Narebska et al (1985Narebska et al ( , 1987aNarebska et al ( ,b, 1995aNarebska et al ( ,b, 1997.…”