Non‐aggregated boron–fluorine derivatives with photodynamic activity

Abstract

Novel non-aggregated boron-fluorine derivatives with large Stokes shift were facilely synthesized and characterized. These dyes show moderate absorptive coefficients and intense fluorescence emission, and excellent photo-stability in solvents and also in solid state. According to X-ray single-crystal analysis, non-covalent intermolecular interactions provide a rigid structure, which inhibits aggregate formation. These non-aggregated dyes can generate singlet oxygen under light irradiation, which makes them good candidates for photodynamic therapy.

A Dication Cross‐Linked Composite Anion‐Exchange Membrane for All‐Vanadium Flow Battery Applications

“…Some studies on the toxicology and the pharmacologic activity of salicylaldimine‐based borate complexes as antifungal compounds have been carried out 152. 153 Other complexes have been used to generate singlet oxygen, and are potentially useful for photodynamic therapy,44 and as photoinitiators in radical polymerization reactions 154…”

Lumineszierende Materialien: Fixierung von π‐konjugierten und heterocyclischen Liganden mit Bor(III)

“…Es wurden einige Untersuchungen zur Toxikologie und pharmakologischen Wirksamkeit von Salicylaldimin‐Borat‐Komplexen als Antimykotika durchgeführt 152. 153 Andere Komplexe werden zur Erzeugung von Singulettsauerstoff genutzt und sind möglicherweise zur photodynamischen Therapie44 und als Photoinitiatoren in radikalischen Polymerisationsreaktionen einsetzbar 154…”

Boron‐Fluorine Photosensitizers for Photodynamic Therapy

“…But typical BODIPY dyes have highly planar structure, and they usually pack tightly in concentrated solution, which imposes a limit that current sensitizers have to be used in dilute solutions. In order to solve this problem, we proposed to use 2-(2 -pyridyl) imidazole derivatives as ligands to coordinate with BF 3 to produce a new class of boron-fluorine dyes (BOPIM, Figure 11) [58]. According to X-ray single crystal diffractions, they form a rigid nonplanar structure through noncovalent intermolecular interactions (B-F⋅ ⋅ ⋅ H, B-F⋅ ⋅ ⋅ C, etc.…”