Non-adrenergic Inhibition of the Electrical Activity of the Antrum Muscle Fibers of the Guinea-Pig Stomach

Ohkawa, Hiromichi; Watanabe, Masayuki

doi:10.1620/tjem.120.11

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2012

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Cited by 4 publications

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“…In the presence of a-and b-adrenergic blockers, ATP and related substances were shown to produce inhibitory effects on the spike activity and generation of slow waves in isolated muscle preparation of the guinea pig antrum, suggesting direct action of ATP and related substances on the antrum muscle (Ohkawa and Watanabe 1976). Subsequent studies give further supporting evidence for purinergic NANC inhibitory transmission in the stomach, including: the fast component of the IJPs is blocked by apamin and suramin (Ohno et al 1996;Xue et al 1996); ATP and analogues mimic the relaxation and hyperpolarisation produced by NANC nerve stimulation.…”

Section: Stomachmentioning

confidence: 96%