We investigate extrinsic wormholelike twist defects that effectively increase the genus of space in lattice versions of multicomponent fractional quantum Hall systems. Although the original band structure is distorted by these defects, leading to localized midgap states, we find that a new lowest flat band representing a higher genus system can be engineered by tuning local single-particle potentials. Remarkably, once local many-body interactions in this new band are switched on, we identify various Abelian and non-Abelian fractional quantum Hall states, whose ground-state degeneracy increases with the number of defects, i.e, with the genus of space. This sensitivity of topological degeneracy to defects provides a "proof of concept" demonstration that genons, predicted by topological field theory as exotic non-Abelian defects tied to a varying topology of space, do exist in realistic microscopic models. Specifically, our results indicate that genons could be created in the laboratory by combining the physics of artificial gauge fields in cold atom systems with already existing holographic beam shaping methods for creating twist defects. Introduction. Extrinsic defects embedded in topologically ordered phases of matter [1-5] may acquire exotic properties [6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22]. Genons [11,12], named after their ability to effectively increase the genus of space thus enhancing the topological degeneracy, are particularly intriguing representatives of this idea and can be visualized as twist defects at the ends of branch cuts connecting separate "world sheets" of different components in the host system. Importantly, the linkage of genons to the topology of space and the underlying topological order establishes them as powerful tools to overcome the long-standing challenge of accessing topological orders on surfaces with tunable genus. It also imparts them with nontrivial quantum dimensions and braiding statistics that are significantly different from those of intrinsic quasiparticles of the host system [12], thus enabling fault tolerant topological quantum computation [23,24] even in Abelian host states without this capability and extending our knowledge of topological order. However, while the beautiful idea of genons is based on topological field theory [11,12] and corroborated by complicated exactly solvable models [6,10,16], its actual relevance to realistic microscopic models has remained open.