Pseudolymphomatous folliculitis is a rare entity included among the cutaneous
pseudolymphomas. A 32-year-old man, with an unremarkable medical history,
presented with a two-month history of an asymptomatic solitary nodule on his
left cheek. Histopathological examination demonstrated a dense nodular and
diffuse dermal lymphocytic infiltrate with numerous histiocytes and dendritic
cells that surrounded hypertrophic hair follicles. Pseudolymphomatous
folliculitis commonly presents in the fourth decade of life, with no sex
predominance, as an asymptomatic, rapidly growing and solitary red dome-shaped
nodule on the face. It has a benign clinical course as the lesions usually
resolve with surgical excision or regress spontaneously after incisional biopsy.
Although there is no report of pseudolymphomatous folliculitis progressing into
lymphoma in the literature, follow-up of these patients is recommended.