mian A. Associations between site of skin lesions and depression, social anxiety, body-related emotions and feelings of stigmatization in psoriasis patients.
Background: Darier's disease (DD) is an autosomal dominant skin disorder which causative gene, ATP2A2, is located at chromosome 12q23-24. The lesions of DD are skin-coloured to brown, hyperkeratotic, greasy papules that coalesce into warty plaques commonly involving the seborrhoeic areas of the trunk and face, especially the scalp margins, temples, ears, and scalp. The most common complaint associated with the disease is itching, with exacerbations attributed to heat, sweating, sunlight, lithium, steroid therapy, stress, and menstruation Objectives: We report a patient with DD treated with topical diclofenac sodium 3%.Methods: We report a 33-year-old patient with Darier's Disease. He was followed in our department since 2009, and we had tried to control several flares of lesions during follow-up, but oral isotretinoin was not tolerated because of adverse effects; and oral doxycycline showed lack of efficacy.At April 2014, patient presented with new lesions, involving anterior chest wall, abdomen, back and shoulders areas. We started with diclofenac sodium 3% in hyaluronic acid 2.5% once daily, only applied at abdomen and anterior chest wall.
Pseudolymphomatous folliculitis is a rare entity included among the cutaneous
pseudolymphomas. A 32-year-old man, with an unremarkable medical history,
presented with a two-month history of an asymptomatic solitary nodule on his
left cheek. Histopathological examination demonstrated a dense nodular and
diffuse dermal lymphocytic infiltrate with numerous histiocytes and dendritic
cells that surrounded hypertrophic hair follicles. Pseudolymphomatous
folliculitis commonly presents in the fourth decade of life, with no sex
predominance, as an asymptomatic, rapidly growing and solitary red dome-shaped
nodule on the face. It has a benign clinical course as the lesions usually
resolve with surgical excision or regress spontaneously after incisional biopsy.
Although there is no report of pseudolymphomatous folliculitis progressing into
lymphoma in the literature, follow-up of these patients is recommended.
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