Nodule de Sœur-Marie-Joseph : quelles implications diagnostiques et thérapeutiques ? À propos de deux cas

Abstract

Les métastases ombilicales des tumeurs viscérales sont très rares et graves vu leur pronostic péjoratif. Elles constituent parfois le seul signe d'appel vers la tumeur primitive, ce qui rend la démarche diagnostique difficile. À cet égard, il nous semble intéressant de vous rapporter deux cas de métastases cutanées ombilicales de tumeurs gastriques colligés dans le service de gastroentérologie du CHU Mohammed-VI. Pour citer cette revue : J. Afr. Hépatol. Gastroentérol. 5 (2011). Mots clés Métastase ombilicale · Cancer gastrique · Chimiothérapie palliativeAbstract Umbilical metastases of the visceral tumours are very rare and associated with a poor prognosis. They sometimes appear as a result of primary tumour, making the diagnosis difficult. In this article, we report two cases of umbilical cutaneous metastases of gastric tumours in the Gastroenterology Department of Mohammed VI Hospital.

A special discovery of pancreatic adenocarcinoma by Sister Mary-Joseph’s Nodule: what is the prognosis?

“…But they can also be associated with squamous cell carcinoma, melanoma or sarcoma. The gastrointestinal tract is the most common origin of the primary tumour followed by gynaecological localization [6] . The most-reported digestive origins in descending order are stomach (26%), colon (10%) and pancreas (7%) [6] .…”

“…The gastrointestinal tract is the most common origin of the primary tumour followed by gynaecological localization [6] . The most-reported digestive origins in descending order are stomach (26%), colon (10%) and pancreas (7%) [6] . Primary tumor cannot be found in 15% of cases [7,8] .…”

Sister Mary Joseph’s Nodule of a Gastric Origin: About a Case and Literature Review

“…The term Nodule of Sister Mary Joseph was first described by a nurse "Sister Mary Joseph Dempsay" who accidentally discovered an umbilical nodule in a patient during preoperative abdominal preparation [1]. This eponymous was first used by Sir Hamilton Bailey in 1949 to describe the entity of umbilical metastatic lesions [2]. The sister mary joseph's nodule is a palpable nodule clinically secondary most often to an abdominopelvic tumor [3].…”

“…In our patient, the nodular umbilical lesion was ulcerative burgeoning and was 5 cm in large diameter. The formal diagnosis is based on the double pathological study: diagnosis when the umbilical nodule is isolated, thus making it possible to determine its primitive or secondary origin and for the purpose of extension assessment allowing to confirm the metastatic character of a primary tumor already known as is the case in our patient who is already followed for gastric cancer [2]. The most common histological type is adenocarcinoma in approximately 75% of cases, more rarely squamous cell carcinoma, undifferentiated cancer or carcinoid tumor [7,10].…”