Nodular scleroderma presenting as multiple spontaneous keloidal scars

Heath, Candrice; David, Jennifer; Taylor, Susan C.

doi:10.1016/j.jaad.2011.06.031

Cited by 5 publications

(7 citation statements)

References 2 publications

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“…Nodular or keloidal scleroderma have been reported in either systemic sclerosis or localized scleroderma, usually 6 months after the presentation of systemic sclerosis [1, 2, 3, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17]. However, also the presence of nodular scleroderma before the onset of systemic sclerosis has been reported [12].…”

Section: Discussionmentioning

confidence: 99%

“…However, also the presence of nodular scleroderma before the onset of systemic sclerosis has been reported [12]. This condition can be found in systemic sclerosis patients either with or without active systemic involvements [1, 2, 8, 11, 12, 13, 14, 15, 16, 17, 18, 19]. …”

Section: Discussionmentioning

confidence: 99%

“…Nodular or keloidal scleroderma usually occur in middle-aged females (Table 1) [1, 4, 8, 11, 12, 13, 14, 16, 17, 18]. Variable histopathologic changes have been reported to include characteristics of keloid or hypertrophic scars, of morphea, or of both morphea and keloid [1, 19].…”

Section: Discussionmentioning

confidence: 99%

“…Several treatment modalities are mentioned in the literature, including topical or intralesional steroids, systemic steroids, topical calcipotriene, psoralen photochemotherapy, cyclosporine, D-penicillamine, methotrexate, extracorporeal photochemotherapy, and excision [1, 2, 4, 11, 12, 13, 14, 15, 16, 17, 18, 29, 30]. However, these treatment modalities have shown unsatisfying results.…”

Section: Discussionmentioning

confidence: 99%

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Scleroderma with Nodular Scleroderma

Srisuttiyakorn

Aunhachoke

2016

Case Rep Dermatol

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Background: Nodular scleroderma is a rare variant of scleroderma which can occur in connection with systemic sclerosis or morphea. A biopsy from the lesion can demonstrate the scleroderma pattern, i.e., keloid pattern or mixed type. Treatment is challenging, and several treatments modalities have been reported with unsatisfactory results. Main Observations: We present a case of systemic sclerosis in a 50-year-old female who developed nodular scleroderma in the absence of deterioration of the scleroderma condition. Although no additional treatment was given, the lesions remained stable without progression. Conclusions: Although this condition is rare, it has been reported sporadically, and clinicians should be able to recognize this variant in cases of scleroderma presenting with firm nodules or plaques.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Scleroderma with Nodular Scleroderma

Srisuttiyakorn

Aunhachoke

2016

Case Rep Dermatol

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“…Keloid formation, instead of scarless wound resolution, is seen in individuals with SSc and is considered a wound healing defect. 5,6 Few objective data exist to compare healing in affected versus unaffected skin, and although scleroderma has been characterized as an excessive wound healing response, 7 distinguishing whether fibrosis plays an active role in delayed resolution of an open wound still needs to be determined.…”

Section: Introductionmentioning

confidence: 99%