Nocardial Scleritis

Microbial scleritis—experience from a developing country

“…Review of literature using PubMed and search using term 'infective scleritis' revealed that even this organism is a rare cause of scleritis. [14][15][16][17][18] High prevalence in the current series could be due to the higher presence of Nocardia in the soil of India. Also, India being an agricultural-based developing economy, has led to greater opportunities for transfer of these organisms from the soil to the eye.…”

“…While literature review suggests a variable response to medical, surgical, and combined treatment regimes, all patients in our series responded favourably to treatment. [14][15][16][17][18] As recommended for severe scleritis refractory to medical treatment, surgical debridement and irrigation of the exposed scleral bed with antibiotics were performed in this series in 14 cases. Surgical debridement not only facilitates the penetration of antibiotics but also debulks the infected scleral tissue.…”

Second report of a Nocardia beijingensis infection in the United States: nodular scleritis with in vitro imipenem resistance

“…Additionally, microbiology testing often yields negative cultures. [12][13][14][15][16] Pseudomonas aeruginosa is the most commonly reported causative organism of infectious scleritis. 11 In this case, 2 cultures were negative before the third showed the organism.…”

“…Surgical intervention is employed in the majority of cases that result in complete cure. 14,15,17,18,20,21 Jain et al maintains that surgical debridement is important in facilitating the penetration of antibiotics and in debulking infected tissue. 20 Despite limited data, we believe that there could be a role for subconjunctival and sub-Tenon's antibiotics, even though we did not use them.…”

Nodular non-necrotising anterior scleritis due to Nocardia nova infection

“…Reported predisposing factors for scleritis due to Nocardia are trauma, cataract surgery, exposed scleral buckle, and contact lens wear. [2][3][4][5][6] We are unaware of a previous report on Nocardia nova infection in the Eye.…”