Microbial scleritis—experience from a developing country

Jain, Vandana; Garg, Prashant; Sharma, Savitri

doi:10.1038/sj.eye.6703099

Cited by 96 publications

(136 citation statements)

References 22 publications

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“…Nocardia are the second most common cause of infectious scleritis in Southern India. 26 The predisposing factors and clinical picture of Nocardia scleritis are almost similar to that of fungal and NTM scleritis.…”

Section: Nocardia and The Eyementioning

confidence: 69%

“…26,27 In a report published by us, 38% cases of infective scleritis were caused by fungi. 26 The fungal infection of sclera commonly occurs following accidental trauma or following variety of surgical procedures, but can also occur as an extension from cornea or choroid and rarely as an endogenous infection. The diagnosis of fungal scleritis is often delayed because the disease in initial stage appears identical to that caused by immune-mediated disease.…”

Section: Scleritismentioning

confidence: 99%

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Fungal, Mycobacterial, and Nocardia infections and the eye: an update

Garg

2011

Eye

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Although relatively uncommon, fungi, atypical Mycobacteria, and Nocardia have been isolated from a variety of infections of eye including keratitis, scleritis, canaliculitis, dacryocystitis, endophthalmitis and orbital cellulites. The organisms typically cause a slowly progressive disease. The diseases caused by the organisms can pose both diagnostic and therapeutic challenges. In this manuscript we will describe updates on important aspects of the ocular infections caused by these organisms.

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Section: Nocardia and The Eyementioning

confidence: 69%

Section: Scleritismentioning

confidence: 99%

Fungal, Mycobacterial, and Nocardia infections and the eye: an update

Garg

2011

Eye

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“…14,15,17,18,20,21 Jain et al maintains that surgical debridement is important in facilitating the penetration of antibiotics and in debulking infected tissue. 20 Despite limited data, we believe that there could be a role for subconjunctival and sub-Tenon's antibiotics, even though we did not use them. There are reports in the literature on the treatment of infectious scleritis and sclerokeratitis that have combined topical, oral, and subconjunctival antibiotics.…”

Section: Discussionmentioning

confidence: 99%

“…Final visual acuity in previous reports ranges from 20/20 to 20/400. 19,20 In cases of infectious scleritis, poorer outcomes are associated with presenting visual acuity worse than 20/200 and concomitant keratitis or endophalmitis.…”

Section: Discussionmentioning

confidence: 99%

Second report of a Nocardia beijingensis infection in the United States: nodular scleritis with in vitro imipenem resistance

et al. 2016

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SummaryWe describe the case of a 52-year-old woman with scleritis caused by an imipenem-resistant strain of Nocardia beijingensis. The patient presented with pain, redness, and nodules on the sclera of 8 weeks' duration. A Gram stain from a nodule on the superonasal aspect of the globe was initially negative. After empiric treatment for an autoimmune etiology, cytopathology confirmed filamentous bacteria. A presumptive diagnosis of Nocardia scleritis was made, and medical management was based on a literature review on treatments for Nocardia infections. Cultures returned confirming Nocardia beijingensis. Antibiotic sensitivity testing confirmed the correct initial management. The patient's scleritis resolved with a good visual outcome.

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“…1 Rhodotorula is a yeast of the family Cryptococcaceae that has been identified as a conjunctival commensal. 3 It has been implicated in canaliculitis, endophthalmitis, and keratitis.…”

Section: Commentmentioning

confidence: 99%