NO signaling in plant immunity: A tale of messengers

Trapet, Pauline; Kulik, Anna; Lamotte, Olivier; Jeandroz, Sylvain; Bourque, Stéphane; Nicolas-Francès, Valérie; Rosnoblet, Claire; Besson-Bard, Angélique; Wendehenne, David

doi:10.1016/j.phytochem.2014.03.015

Cited by 79 publications

(45 citation statements)

References 96 publications

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“…Furthermore, the actions of NO-derived chemical species are, in part, mediated by posttranslational protein modifications, including tyrosine nitration, Cys-nitrosation, and metal-nitrosylation. Also, plant and animal cells share key enzymes involved in the regulation of NO effects such as nitrosoglutathione reductase, thioredoxins, thioredoxin reductases, and hemoglobin (39)(40)(41)(42)(43). In animals, constitutive NOSes are part of protein complexes that play a fundamental role in transducing NO signaling activities.…”

Section: +mentioning

confidence: 99%

Occurrence, structure, and evolution of nitric oxide synthase–like proteins in the plant kingdom

et al. 2016

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Nitric oxide (NO) signaling regulates various physiological processes in both animals and plants. In animals, NO synthesis is mainly catalyzed by NO synthase (NOS) enzymes. Although NOS-like activities that are sensitive to mammalian NOS inhibitors have been detected in plant extracts, few bona fide plant NOS enzymes have been identified. We searched the data set produced by the 1000 Plants (1KP) international consortium for the presence of transcripts encoding NOS-like proteins in over 1000 species of land plants and algae. We also searched for genes encoding NOS-like enzymes in 24 publicly available algal genomes. We identified no typical NOS sequences in 1087 sequenced transcriptomes of land plants. In contrast, we identified NOS-like sequences in 15 of the 265 algal species analyzed. Even if the presence of NOS enzymes assembled from multipolypeptides in plants cannot be conclusively discarded, the emerging data suggest that, instead of generating NO with evolutionarily conserved NOS enzymes, land plants have evolved finely regulated nitrate assimilation and reduction processes to synthesize NO through a mechanism different than that in animals.

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Section: +mentioning

confidence: 99%

Occurrence, structure, and evolution of nitric oxide synthase–like proteins in the plant kingdom

et al. 2016

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“…While reactive oxygen species (ROS)-mediated defense responses are well documented (Dietz, 2003;Torres, 2010;Mittler et al, 2011;O'Brien et al, 2012;Frederickson Matika and Loake, 2014;Lehmann et al, 2015;Trapet et al, 2015), the precise role of NAD in ROSrelated plant immunity remains poorly understood. ROS bursts contribute to basal defense responses after the perception of pathogen-associated molecular patterns (PAMPs), which are conserved molecules for a whole class of microbes, or via damage-associated molecular patterns (DAMPs), which are signals of cell disintegration (Heil and Land, 2014;Macho and Zipfel, 2014).…”

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confidence: 99%

NAD Acts as an Integral Regulator of Multiple Defense Layers

et al. 2016

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(J.T.).Pyridine nucleotides, such as NAD, are crucial redox carriers and have emerged as important signaling molecules in stress responses. Previously, we have demonstrated in Arabidopsis (Arabidopsis thaliana) that the inducible NAD-overproducing nadC lines are more resistant to an avirulent strain of Pseudomonas syringae pv tomato (Pst-AvrRpm1), which was associated with salicylic acid-dependent defense. Here, we have further characterized the NAD-dependent immune response in Arabidopsis. Quinolinate-induced stimulation of intracellular NAD in transgenic nadC plants enhanced resistance against a diverse range of (a)virulent pathogens, including Pst-AvrRpt2, Dickeya dadantii, and Botrytis cinerea. Characterization of the redox status demonstrated that elevated NAD levels induce reactive oxygen species (ROS) production and the expression of redox marker genes of the cytosol and mitochondrion. Using pharmacological and reverse genetics approaches, we show that NAD-induced ROS production functions independently of NADPH oxidase activity and light metabolism but depends on mitochondrial respiration, which was increased at higher NAD. We further demonstrate that NAD primes pathogen-induced callose deposition and cell death. Mass spectrometry analysis reveals that NAD simultaneously induces different defense hormones and that the NAD-induced metabolic profiles are similar to those of defense-expressing plants after treatment with pathogen-associated molecular patterns. We thus conclude that NAD triggers metabolic profiles rather similar to that of pathogen-associated molecular patterns and discuss how signaling cross talk between defense hormones, ROS, and NAD explains the observed resistance to pathogens.

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“…It is well known that many of these stresses may lead to an oxidative stress characterized by uncontrollable overproduction of ROS that generates molecular damage in proteins, lipids, and nucleic acids. However, it is also well documented that all these stresses trigger an imbalance of RNS production [8,61,62]. Nevertheless, in all these mechanisms of response it is important to elucidate if any of these reactive species act as signal molecules or could promote cellular damage.…”

Section: No Is Involved In the Mechanism Of Response Against Both Abimentioning

confidence: 99%

Assessing Nitric Oxide (NO) in Higher Plants: An Outline

Corpas

Palma

2018

Nitrogen

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Nitric oxide (NO) is a free radical and a component of the N-cycle. Nevertheless, NO is likewise endogenously produced inside plant cells where it participates in a myriad of physiological functions, as well as in the mechanism of response against abiotic and biotic stresses. At biochemical level, NO has a family of derived molecules designated as reactive nitrogen species (RNS) which finally can interact with different bio-macromolecules including proteins, lipids, and nucleic acids affecting their functions. The present review has the goal to provide a comprehensive and quick overview of the relevance of NO in higher plants, especially for those researchers who are not familiar in this research area in higher plants.

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NO signaling in plant immunity: A tale of messengers

Cited by 79 publications

References 96 publications

Occurrence, structure, and evolution of nitric oxide synthase–like proteins in the plant kingdom

Occurrence, structure, and evolution of nitric oxide synthase–like proteins in the plant kingdom

NAD Acts as an Integral Regulator of Multiple Defense Layers

Assessing Nitric Oxide (NO) in Higher Plants: An Outline

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