No differences in hemodynamics, ventricular function, and oxygen delivery in septic and nonseptic patients with the adult respiratory distress syndrome

Acute respiratory distress syndrome in a community hospital ICU

“…Our (day 1) Murray scores of 2.4 ± 0.6 and 2.7 ± 0.3 indicate moderately severe lung injury in both survivors and non-survivors [18]. The APACHE II scores in our study were comparable to those already reported in the literature, with those studies having similar or worse survival figures [27,28]. The PaO 2 /FIO 2 ratio at the time of diagnosis of ARDS was not significantly different for survivors versus non-survivors.…”

Hemodynamic profile in severe ARDS: results of the European Collaborative ARDS Study

“…Although there is general agreement that ARDS is associated with moderate pulmonary hypertension [7], high cardiac output [8], and increased metabolic requirements [9], it is unknown whether ARDS is characterized by a specific hemodynamic profile or whether the hemodynamic status merely reflects the abnormality that caused ARDS [10]. The lack of a clear understanding of the interrelationships between ARDS and hemodynamics is a major obstacle to the interpretation and comparisons of the results of clinical studies.…”

Cardiovascular Management of ARDS

“…Ronco and colleagues found no differences in hemodynamics, ventricular function, and oxygen delivery and consumption between septic and nonseptic ARDS patients, suggesting that ARDS patients generally display a hemodynamic pattern similar to that of septic patients. 5 Indeed, septic shock is present in up to 64% of patients at onset of ARDS 6 and is an independent predictor of mortality. 7,8 Thus, bedside clinical examination of an adequately resuscitated ARDS patient may show evidence of a high cardiac output state disclosed by warm extremities, bounding peripheral pulses, rapid nailbed return, crisp heart sounds, and a wide pulse pressure.…”